Use of Antimicrobial Metaphylaxis for the Control of Bovine Respiratory Disease in High-Risk Cattle

Despite research and increased availability of antimicrobials, the prevalence and challenges associated with bovine respiratory disease (BAD) in stocker and feedlot operations remain. Preconditioned calves can better handle the transition from the origin ranch to the feedlot, yet there is incentive for buyers to purchase high-risk cattle at a reduced cost, and this is influenced by the proven efficacy and availability of antimicrobial metaphylaxis. The poor sensitivity of current BAD field diagnostic methods, typical pathogenesis of BAD, and labor issues are additional reasons to use metaphylaxis. Nevertheless, practitioners should consider comprehensive and novel approaches to judiciously guide decisions on metaphylactic use of antimicrobials.