Palladium-catalyzed synthesis of 3-(alkylamino)isoindolin-1-ones by carbonylative cyclization of 2-bromobenzaldehyde with primary amines

被引:35
作者
Cho, CS
Jiang, LH
Lee, DY
Shim, SC
Lee, HS
Cho, SD
机构
[1] CATHOLIC UNIV,DEPT CHEM,KYONGSAN 712702,SOUTH KOREA
[2] CHOSUN UNIV,DEPT CHEM,KWANGJU 501759,SOUTH KOREA
关键词
D O I
10.1002/jhet.5570340446
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
2-Bromobenzaldehyde reacts with an excess of primary amines under a carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3-(alkylamino)isoindolin-1-ones in good yields.
引用
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页码:1371 / 1374
页数:4
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