Enantioselective total syntheses of cedrelin A and methylated paralycolin B using Pd-catalyzed asymmetric intramolecular Friedel0Crafts allylic alkylation of phenols

被引：11
作者：
Suzuki, Yuta [1 ]
Matsuo, Nobuaki [1 ]
Nemoto, Tetsuhiro [1 ]
Hamada, Yasumasa [1 ]
机构：
[1] Chiba Univ, Grad Sch Pharmaceut Sci, Chuo Ku, Chiba 2608675, Japan
来源：
TETRAHEDRON | 2013年 / 69卷 / 29期
关键词：
Asymmetric synthesis; Dihydrophenanthrenes; Friedel-Crafts alkylation; Palladium; Total synthesis; CROSS-COUPLING REACTIONS; DIHYDROPHENANTHRENE; DEAROMATIZATION; ALLYLATION;
D O I：
10.1016/j.tet.2013.05.007
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
We report the first enantioselective total syntheses of cedrelin A and methylated paralycolin B, wherein Pd-catalyzed asymmetric intramolecular Friedel-Crafts allylic alkylation of phenols was the key step. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5913 / 5919
页数：7
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