Synthesis, characterization and biological studies of new Schiff bases and azetidinones derived from propionic acid derivatives

被引:0
作者
Fuloria, Neeraj Kumar [1 ]
Singh, Vijender [1 ]
Shaharyar, Mohd [1 ]
Ali, Mohammad [1 ]
机构
[1] Rameesh Inst Vocat & Tech Educat, Dept Pharm, Greater Noida 201306, India
关键词
phenyl propionohydrazide; methyl phenyl propanoate; Schiff base; azetidinones; antibacterial and antifungal activity;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Phenyl propionohydrazide (2), a hydrazinated derivative of methyl phenyl propanoate (1), when refluxed with aromatic aldehydes yielded Schiff bases 3A-E, which on subsequent cyclization with triethylamine and chloroacetylehloride yielded azetidinones 4A-E. The novel series of compounds were elucidated on the basis of spectral studies and screened for antibacterial and antifungal studies.
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页码:6457 / 6462
页数:6
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