Impact of photon cross section uncertainties on Monte Carlo-determined depth-dose distributions

被引:3
作者
Aguirre, E. [1 ]
David, M. [2 ]
deAlmeida, C. E. [2 ]
Bernal, M. A. [1 ]
机构
[1] Univ Estadual Campinas, Inst Fis Gleb Wataghin, BR-13081970 Campinas, SP, Brazil
[2] Univ Estado Rio de Janeiro, Lab Ciencias Radiol, Rio De Janeiro, RJ, Brazil
来源
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS | 2016年 / 32卷 / 09期
基金
巴西圣保罗研究基金会;
关键词
Monte Carlo; Systematic uncertainty; Photon cross sections; Dose distribution;
D O I
10.1016/j.ejmp.2016.08.002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
This work studies the impact of systematic uncertainties associated to interaction cross sections on depth dose curves determined by Monte Carlo simulations. The corresponding sensitivity factors are quantified by changing cross sections by a given amount and determining the variation in the dose. The influence of total and partial photon cross sections is addressed. Partial cross sections for Compton and Rayleigh scattering, photo-electric effect, and pair production have been accounted for. The PENELOPE code was used in all simulations. It was found that photon cross section sensitivity factors depend on depth. In addition, they are positive and negative for depths below and above an equilibrium depth, respectively. At this depth, sensitivity factors are null. The equilibrium depths found in this work agree very well with the mean free path of the corresponding incident photon energy. Using the sensitivity factors reported here, it is possible to estimate the impact of photon cross section uncertainties on the uncertainty of Monte Carlo-determined depth dose curves. (C) 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:1065 / 1071
页数:7
相关论文
共 21 条
[1]   Towards a quantitative, measurement-based estimate of the uncertainty in photon mass attenuation coefficients at radiation therapy energies [J].
Ali, E. S. M. ;
Spencer, B. ;
McEwen, M. R. ;
Rogers, D. W. O. .
PHYSICS IN MEDICINE AND BIOLOGY, 2015, 60 (04) :1641-1654
[2]  
[Anonymous], 2008, TECH REP
[3]  
Berger M, 1999, CRC HDB CHEM PHYS
[4]   Track structure modeling in liquid water: A review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit [J].
Bernal, M. A. ;
Bordage, M. C. ;
Brown, J. M. C. ;
Davidkova, M. ;
Delage, E. ;
El Bitar, Z. ;
Enger, S. A. ;
Francis, Z. ;
Guatelli, S. ;
Ivanchenko, V. N. ;
Karamitros, M. ;
Kyriakou, I. ;
Maigne, L. ;
Meylan, S. ;
Murakami, K. ;
Okada, S. ;
Payno, H. ;
Perrot, Y. ;
Petrovic, I. ;
Pham, Q. T. ;
Ristic-Fira, A. ;
Sasaki, T. ;
Stepan, V. ;
Tran, H. N. ;
Villagrasa, C. ;
Incerti, S. .
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 2015, 31 (08) :861-874
[5]   Brachytherapy dosimetry of 125I and 103Pd sources using an updated cross section library for the MCNP Monte Carlo transport code [J].
Bohm, TD ;
DeLuca, PM ;
DeWerd, LA .
MEDICAL PHYSICS, 2003, 30 (04) :701-711
[6]  
Breismeister JF, 1993, LA12625 LOS AL NAT L
[7]   An analysis of MCNP cross-sections and tally methods for low-energy photon emitters [J].
DeMarco, JJ ;
Wallace, RE ;
Boedeker, K .
PHYSICS IN MEDICINE AND BIOLOGY, 2002, 47 (08) :1321-1332
[8]  
Goorley J.T., 2014, LA-UR-14-24680
[9]   Review of photon interaction cross section data in the medical and biological context [J].
Hubbell, JH .
PHYSICS IN MEDICINE AND BIOLOGY, 1999, 44 (01) :R1-R22
[10]   Monte Carlo calculations of kQ, the beam quality conversion factor [J].
Muir, B. R. ;
Rogers, D. W. O. .
MEDICAL PHYSICS, 2010, 37 (11) :5939-5950