Evidence-based treatments of addiction

被引：86
作者：
O'Brien, Charles P. [1 ]
机构：
[1] Univ Penn, Dept Psychiat, Philadelphia, PA 19104 USA
来源：
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 2008年 / 363卷 / 1507期
关键词：
addiction; relapse; withdrawal; endophenotype;
D O I：
10.1098/rstb.2008.0105
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Both pharmacotherapy and behavioural treatment are required to relieve the symptoms of addictive disorders. This paper reviews the evidence for the benefits of pharmacotherapy and discusses mechanisms where possible. Animal models of addiction have led to some medications that are effective in reducing symptoms and improving function but they do not produce a cure. Addiction is a chronic disease that tends to recur when treatment is stopped; thus, long-term treatment is recommended.
引用
收藏
页码：3277 / 3286
页数：10
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