Light-Controlled Toxicity of Engineered Amyloid β-Peptides

被引:9
作者
Hoppmann, Christian [1 ]
Barucker, Christian [2 ,3 ]
Lorenz, Dorothea [1 ]
Multhaup, Gerd [2 ,3 ]
Beyermann, Michael [1 ]
机构
[1] Leibniz Inst Mol Pharmakol FMP, Dept Biol Chem, D-13125 Berlin, Germany
[2] Free Univ Berlin, Inst Chem & Biochem, Fac Biol Chem Pharm, D-14195 Berlin, Germany
[3] McGill Univ, Dept Pharmacol & Therapeut, Montreal, PQ H3G 1Y6, Canada
关键词
Alzheimer's disease; amyloid beta-peptides; azobenzene; isomerization; light-directed disassembly; ALZHEIMERS-DISEASE; CONFORMATIONAL TRANSITION; ION CHANNELS; OLIGOMERS; CONVERSION; MECHANISM; FIBRILS; HAIRPIN;
D O I
10.1002/cbic.201200605
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
[No abstract available]
引用
收藏
页码:2657 / 2660
页数:4
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