HYPOXIA-INDUCED DEATH OF GLIOBLASTOMA CELLS: TP53-INDUCED GLYCOLYSIS AND APOPTOSIS REGULATOR (TIGAR) HARMONIZES CELLULAR REDOX HOMEOSTASIS AND PROTECTS GLIOMA CELLS FROM HYPOXIA AND STARVATION BY UPREGULATION OF THE PENTOSE PHOSPHATE PATHWAY

被引：0
|
作者：
Wanka, C. [1 ]
Steinbach, J. P. [1 ]
Rieger, J. [1 ]
机构：
[1] Dr Senckenberg Inst Neurooncol, Frankfurt, Germany
来源：
NEURO-ONCOLOGY | 2012年 / 14卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：2 / 2
页数：1
相关论文
共 22 条
  • [1] Tp53-induced Glycolysis and Apoptosis Regulator (TIGAR) Protects Glioma Cells from Starvation-induced Cell Death by Up-regulating Respiration and Improving Cellular Redox Homeostasis
    Wanka, Christina
    Steinbach, Joachim P.
    Rieger, Johannes
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (40) : 33436 - 33446
  • [2] Knockdown of the TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Sensitizes Glioma Cells to Hypoxia, Irradiation and Temozolomide
    Maurer, Gabriele D.
    Heller, Sonja
    Wanka, Christina
    Rieger, Johannes
    Steinbach, Joachim P.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (05):
  • [3] TP53-induced glycolysis and apoptosis regulator (TIGAR) induces NADPH production and growth in nasopharyngeal carcinoma cells
    Lam, Emily K. Y.
    Lui, Vivian W. Y.
    Wong, Elaine Y. L.
    Lau, Cecilia P. Y.
    Nong, Cesar S. C.
    Hui, Edwin P.
    Chan, Andrew S. K.
    Tsao, Sai Wah
    Mills, Gordon B.
    Chan, Anthony T. C.
    CANCER RESEARCH, 2011, 71
  • [4] TP53 induced glycolysis and apoptosis regulator (TIGAR) knockdown results in radiosensitization of glioma cells
    Pena-Rico, Miguel A.
    Nieves Calvo-Vidal, Maria
    Villalonga-Planells, Ruth
    Martinez-Soler, Fina
    Gimenez-Bonafe, Pepita
    Navarro-Sabate, Aurea
    Tortosa, Avelina
    Bartrons, Ramon
    Manzano, Anna
    RADIOTHERAPY AND ONCOLOGY, 2011, 101 (01) : 132 - 139
  • [5] Radiosensitization of glioma cells by TP53-induced glycolysis and apoptosis regulator knockdown is dependent on thioredoxin-1 nuclear translocation
    Zhang, Haowen
    Gu, Cheng
    Yu, Jiahua
    Wang, Zhongmin
    Yuan, Xiaopeng
    Yang, Lei
    Wang, Jie
    Jia, Yanshuang
    Liu, Jianjun
    Liu, Fenju
    FREE RADICAL BIOLOGY AND MEDICINE, 2014, 69 : 239 - 248
  • [6] The Expression of TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Can Be Controlled by the Antioxidant Orchestrator NRF2 in Human Carcinoma Cells
    Simon-Molas, Helga
    Sanchez-de-Diego, Cristina
    Navarro-Sabate, Aurea
    Castano, Esther
    Ventura, Francesc
    Bartrons, Ramon
    Manzano, Anna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (03)
  • [7] Molecular cloning and modeling of the Tp53-induced glycolysis and apoptotic regulator (TIGAR) from the Pacific white shrimp Litopenaeus vannamei and its expression in response to hypoxia
    Camacho-Jimenez, Laura
    Felix-Portillo, Monserrath
    Nunez-Hernandez, Dahlia M.
    Yepiz-Plascencia, Gloria
    FISH & SHELLFISH IMMUNOLOGY, 2019, 93 : 484 - 491
  • [8] Upregulation of HIF-1α protects neuroblastoma cells from hypoxia-induced apoptosis in a RhoA-dependent manner
    Yin, Cui-Ping
    Guan, Shang-Hui
    Zhang, Bo
    Wang, Xue-Xin
    Yue, Shou-Wei
    MOLECULAR MEDICINE REPORTS, 2015, 12 (05) : 7123 - 7131
  • [9] Inhibition of epidermal growth factor receptor signaling protects human malignant glioma cells from hypoxia-induced cell death
    Steinbach, JP
    Klumpp, A
    Wolburg, H
    Weller, M
    CANCER RESEARCH, 2004, 64 (05) : 1575 - 1578
  • [10] Inhibition of mTOR signaling protects human glioma cells from hypoxia-induced cell death in an autophagy-independent manner
    Iris Divé
    Kevin Klann
    Jonas B. Michaelis
    Dennis Heinzen
    Joachim P. Steinbach
    Christian Münch
    Michael W. Ronellenfitsch
    Cell Death Discovery, 8
123