Impact of Regional Vein Thrombosis in Patients with Klebsiella pneumoniae Liver Abscess

被引：17

作者：

Molton, James S. ^{[1
,2
]}

Chee, Yen Lin ^{[2
,3
]}

Hennedige, Tiffany P. ^{[4
]}

Venkatesh, Sudhakar K. ^{[5
]}

Archuleta, Sophia ^{[1
,2
]}

机构：

[1] Natl Univ Hlth Syst, Univ Med Cluster, Singapore, Singapore

[2] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore 117595, Singapore

[3] Natl Univ Hlth Syst, Dept Hematol Oncol, Singapore, Singapore

[4] Natl Univ Hlth Syst, Dept Diagnost Imaging, Singapore, Singapore

[5] Mayo Clin, Dept Radiol, Rochester, MN USA

来源：

PLOS ONE | 2015年 / 10卷 / 10期

关键词：

TAIWAN;

D O I：

10.1371/journal.pone.0140129

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Klebsiella liver abscess (KLA) is an emerging infection in Asia caused by hypermucoviscous strains of Klebsiella pneumoniae. It is associated with thrombophlebitis of portal and hepatic veins. The natural history and role of anticoagulation for this regional thrombophlebitis is unclear. In a retrospective study of 169 subjects with KLA over 7 years, thrombophlebitis was identified in 53/169 (31.4%). Only 1 received therapeutic anticoagulation. Despite this 30/49 (73.2%) of those with follow up scan available showed improvement or recanalization (mean duration between scans 44 days). Abscess resolution was associated with improvement in thrombophlebitis.

引用

页数：5

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