Morphological and functional alterations of nailfold capillaries in a patient with dermatomyositis

被引:14
作者
Klyscz, T
Bogenschutz, O
Junger, M
Rassner, G
机构
来源
HAUTARZT | 1996年 / 47卷 / 04期
关键词
dermatomyositis; capillary microscopy; fluorescence-videomicroscopy; microangiopathy; lymphatic drainage;
D O I
10.1007/s001050050417
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We report on a 70-year-old female patient with dermatomyositis. The connective tissue vascular bed was studied with capillaroscopy to evaluate morphological and functional changes of skin capillaries. Capillaroscopic findings showed morphological alterations such as rarefication of capillaries, avascular fields and tortuosity of nailfold capillaries. In addition, fluorescence-videomicroscopy showed pathologically increased transcapillary diffusion of dye in the apex region of nutritive skin capillaries. Increased capillary leakage probably contributed to the developement of oedema in our patient. Immunosupressive therapy combined with intensified manual lymphatic drainage was successful.
引用
收藏
页码:289 / 293
页数:5
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