Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

被引：1564

作者：

Arnison, Paul G. ^{[3
]}

Bibb, Mervyn J. ^{[4
]}

Bierbaum, Gabriele

Bowers, Albert A. ^{[6
]}

Bugni, Tim S. ^{[7
]}

Bulaj, Grzegorz ^{[8
]}

Camarero, Julio A. ^{[9
,10
]}

Campopiano, Dominic J. ^{[11
]}

Challis, Gregory L. ^{[12
]}

Clardy, Jon ^{[13
]}

Cotter, Paul D. ^{[14
,15
]}

Craik, David J. ^{[16
]}

Dawson, Michael ^{[17
]}

Dittmann, Elke ^{[18
]}

Donadio, Stefano ^{[19
]}

Dorrestein, Pieter C. ^{[20
]}

Entian, Karl-Dieter ^{[21
]}

Fischbach, Michael A. ^{[22
]}

Garavelli, John S. ^{[23
]}

Goeransson, Ulf ^{[24
]}

Gruber, Christian W. ^{[25
]}

Haft, Daniel H. ^{[26
]}

Hemscheidt, Thomas K. ^{[27
]}

Hertweck, Christian ^{[28
]}

Hill, Colin ^{[15
,29
]}

Horswill, Alexander R. ^{[30
]}

Jaspars, Marcel ^{[31
]}

Kelly, Wendy L. ^{[32
,33
]}

Klinman, Judith P. ^{[34
]}

Kuipers, Oscar P. ^{[35
]}

Link, A. James ^{[36
]}

Liu, Wen ^{[37
]}

Marahiel, Mohamed A. ^{[38
]}

Mitchell, Douglas A. ^{[1
,39
,40
]}

Moll, Gert N. ^{[41
]}

Moore, Bradley S. ^{[42
]}

Mueller, Rolf ^{[43
]}

Nair, Satish K. ^{[44
]}

Nes, Ingolf F. ^{[45
]}

Norris, Gillian E. ^{[46
]}

Olivera, Baldomero M. ^{[47
]}

Onaka, Hiroyasu ^{[48
]}

Patchett, Mark L. ^{[46
]}

Piel, Joern ^{[49
,50
]}

Reaney, Martin J. T. ^{[51
]}

Rebuffat, Sylvie ^{[52
]}

Ross, R. Paul ^{[14
,15
]}

Sahl, Hans-Georg ^{[5
]}

Schmidt, Eric W. ^{[8
,47
]}

Selsted, Michael E. ^{[53
]}

机构：

[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA

[2] Univ Illinois, Howard Hughes Med Inst, Urbana, IL 61801 USA

[3] Bot Alternat Inc, Prairie Plant Syst Inc, Saskatoon, SK S7H 0W2, Canada

[4] John Innes Ctr, Dept Mol Microbiol, Norwich NR4 7UH, Norfolk, England

[5] Univ Bonn, Inst Med Microbiol Immunol & Parasitol, Pharmaceut Microbiol Sect, Bonn, Germany

[6] Univ N Carolina, UNC Eshelman Sch Pharm, Div Chem Biol & Med Chem, Chapel Hill, NC 27599 USA

[7] Univ Wisconsin, Div Pharmaceut Sci, Madison, WI 53705 USA

[8] Univ Utah, Dept Med Chem, Salt Lake City, UT 84112 USA

[9] Univ So Calif, Dept Pharmacol & Pharmaceut Sci, Los Angeles, CA 90033 USA

[10] Univ So Calif, Dept Chem, Los Angeles, CA 90033 USA

[11] Univ Edinburgh, Sch Chem, EaStCHEM, Edinburgh EH9 3JJ, Midlothian, Scotland

[12] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

[13] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA

[14] Teagasc Food Res Ctr, Fermoy, Cork, Ireland

[15] Natl Univ Ireland Univ Coll Cork, Alimentary Pharmabiot Ctr, Cork, Ireland

[16] Univ Queensland, Inst Mol Biosci, Brisbane, Qld 4072, Australia

[17] Novacta Biosyst Ltd, UH Innovat Ctr, Hatfield AL10 9AB, Herts, England

[18] Univ Potsdam, Inst Biochem & Biol, D-14476 Potsdam, Germany

[19] NAICONS Scrl, I-20138 Milan, Italy

[20] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA

[21] Goethe Univ Frankfurt, Inst Mol Biosci, D-60438 Frankfurt, Germany

[22] Univ Calif San Francisco, Calif Inst Quantitat Biosci, Dept Bioengn & Therapeut Sci, San Francisco, CA 94158 USA

[23] Univ Delaware, Delaware Biotechnol Inst, Ctr Bioinformat & Computat Biol, Newark, DE 19711 USA

[24] Uppsala Univ, Dept Med Chem, Div Pharmacognosy, SE-75123 Uppsala, Sweden

[25] Med Univ Vienna, Ctr Physiol & Pharmacol, A-1090 Vienna, Austria

[26] J Craig Venter Inst, Rockville, MD 20850 USA

[27] Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA

[28] Leibniz Inst Nat Prod Res & Infect Biol HKI, D-07745 Jena, Germany

[29] Natl Univ Ireland Univ Coll Cork, Dept Microbiol, Cork, Ireland

[30] Univ Iowa, Carver Coll Med, Dept Microbiol, Iowa City, IA 52242 USA

[31] Univ Aberdeen, Dept Chem, Aberdeen AB24 3UE, Scotland

[32] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

[33] Georgia Inst Technol, Parker H Petit Inst Bioengn & Biosci, Atlanta, GA 30332 USA

[34] Univ Calif Berkeley, Dept Chem, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

[35] Univ Groningen, NL-9747 AG Groningen, Netherlands

[36] Princeton Univ, Dept Chem & Biol Engn, Princeton, NJ 08544 USA

[37] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Bioorgan & Nat Prod Chem, Shanghai 200032, Peoples R China

[38] Univ Marburg, Fachbereich Chem Biochem, D-35032 Marburg, Germany

[39] Univ Illinois, Dept Microbiol, Urbana, IL 61801 USA

[40] Univ Illinois, Inst Genom Biol, Urbana, IL 61801 USA

[41] Lanthiopharma, NL-9747 AG Groningen, Netherlands

[42] Univ Calif San Diego, Scripps Inst Oceanog, Ctr Marine Biotechnol & Biomed, La Jolla, CA 92093 USA

[43] Univ Saarland, Dept Microbial Nat Prod, Helmholtz Ctr Infect Res HZI, Helmholtz Inst Pharmaceut Res Saarland HIPS, D-66123 Saarbrucken, Germany

[44] Univ Illinois, Dept Biochem, Ctr Biophys & Computat Biol, Urbana, IL 61801 USA

[45] Norwegian Univ Life Sci, Dept Chem Biotechnol & Food Sci, Lab Microbial Gene Technol, N-1432 As, Norway

[46] Massey Univ, Inst Mol BioSci, Palmerston North, New Zealand

[47] Univ Utah, Dept Biol, Salt Lake City, UT 84112 USA

[48] Toyama Prefectural Univ, Biotechnol Res Ctr, Toyama, Japan

[49] Univ Bonn, Kekule Inst Organ Chem & Biochem, D-53121 Bonn, Germany

[50] ETH, Inst Microbiol, CH-8093 Zurich, Switzerland

来源：

NATURAL PRODUCT REPORTS | 2013年 / 30卷 / 01期

基金：

美国国家科学基金会;

关键词：

BIOSYNTHETIC GENE-CLUSTER; PROMOTES SECONDARY METABOLISM; CYCLOTIDE CYCLOVIOLACIN O2; IN-VITRO RECONSTITUTION; STREPTOMYCES SP RE-701; NATRIURETIC-FACTOR ANF; GENOME-MINING APPROACH; AMINOACYL-TRANSFER-RNA; ELONGATION-FACTOR-G; LASSO PEPTIDE;

D O I：

10.1039/c2np20085f

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review presents recommended nomenclature for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), a rapidly growing class of natural products. The current knowledge regarding the biosynthesis of the >20 distinct compound classes is also reviewed, and commonalities are discussed.

引用

页码：108 / 160

页数：53

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