Meiotic DSBs and the control of mammalian recombination

被引：4

作者：

Paigen, Kenneth ^{[1
]}

Petkov, Petko ^{[1
]}

机构：

[1] Jackson Lab, Bar Harbor, ME 04609 USA

来源：

CELL RESEARCH | 2012年 / 22卷 / 12期

关键词：

HISTONE H3 METHYLTRANSFERASE; PRDM9; HOTSPOTS; GENOME; MOUSE; GENE; EVOLUTION; MICE;

D O I：

10.1038/cr.2012.109

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The laboratories of Galina Petukhova and R Daniel Camerini-Otero have achieved significant technical advances in determining the genome-wide sites of DNA double-strand breaks (DSBs) where the process of genetic exchange between chromatids during meiosis begins. Applying the new approaches to male meiosis in mice, their experimental results considerably increase our insights into the nature and regulation of these processes. © 2012 IBCB, SIBS, CAS All rights reserved.

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收藏

页码：1624 / 1626

页数：3

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