Untranslated regions of mRNAs

被引：764

作者：

Mignone, Flavio ^{[1
]}

Gissi, Carmela ^{[1
]}

Liuni, Sabino ^{[2
]}

Pesole, Graziano ^{[1
]}

机构：

[1] Univ Milan, Dipartimento Fisiol & Biochim Gen, Via Celoria 26, I-20133 Milan, Italy

[2] Ctr Studio Mitocondri & Metab Energet, I-70126 Bari, Italy

来源：

GENOME BIOLOGY | 2002年 / 3卷 / 03期

关键词：

Internal Ribosome Entry Site; Stable Secondary Structure; Iron Responsive Element; Internal Ribosome Entry Site Element; Codon Context;

D O I：

10.1186/gb-2002-3-3-reviews0004

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Gene expression is finely regulated at the post-transcriptional level. Features of the untranslated regions of mRNAs that control their translation, degradation and localization include stem-loop structures, upstream initiation codons and open reading frames, internal ribosome entry sites and various cis-acting elements that are bound by RNA-binding proteins.

引用

页数：10

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