Prophylactic use of sublingual allergen immunotherapy in high-risk children: A pilot study

被引：71

作者：

Holt, Patrick G. ^{[1
,2
]}

Sly, Peter D. ^{[3
]}

Sampson, Hugh A. ^{[4
]}

Robinson, Phil ^{[5
,6
]}

Loh, Richard ^{[7
]}

Lowenstein, Henning ^{[8
]}

Calatroni, Agustin ^{[9
]}

Sayre, Peter ^{[10
,11
]}

机构：

[1] Univ Western Australia, Telethon Inst Child Hlth Res, Perth, WA 6009, Australia

[2] Univ Western Australia, Ctr Child Hlth Res, Perth, WA 6009, Australia

[3] Univ Queensland, Queensland Childrens Med Res Inst, Royal Childrens Hosp, Brisbane, Qld, Australia

[4] Mt Sinai Sch Med, New York, NY USA

[5] Royal Childrens Hosp, Murdoch Childrens Res Inst, Melbourne, Vic, Australia

[6] Univ Melbourne, Melbourne, Vic, Australia

[7] Princess Margaret Hosp, Child & Adolescent Hlth Serv, Subiaco, WA, Australia

[8] ALK Abello AS, Horsholm, Denmark

[9] Rho Fed Syst, Chapel Hill, NC USA

[10] Immune Tolerance Network, San Francisco, CA USA

[11] Univ Calif San Francisco, San Francisco, CA 94143 USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2013年 / 132卷 / 04期

关键词：

RESPONSES; SENSITIZATION; CELLS;

D O I：

10.1016/j.jaci.2013.04.049

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：991 / 993

页数：4

共 9 条

[1] Early allergen exposure, skin prick responses, and atopic wheeze at age 5 in English children: a cohort study [J].

Cullinan, P ;

MacNeill, SJ ;

Harris, JM ;

Moffat, S ;

White, C ;

Mills, P ;

Taylor, AJN .

THORAX, 2004, 59 (10) :855-861

[2] SQ-standardized sublingual grass immunotherapy: Confirmation of disease modification 2 years after 3 years of treatment in a randomized trial [J].

Durham, Stephen R. ;

Emminger, Waltraud ;

Kapp, Alexander ;

de Monchy, Jan G. R. ;

Rak, Sabina ;

Scadding, Glenis K. ;

Wurtzen, Peter A. ;

Andersen, Jens S. ;

Tholstrup, Bente ;

Riis, Bente ;

Dahl, Ronald .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2012, 129 (03) :717-U184

[3] Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study [J].

Holt, Patrick G. ;

Rowe, Julie ;

Kusel, Merci ;

Parsons, Faith ;

Hollams, Elysia M. ;

Bosco, Anthony ;

McKenna, Kathy ;

Subrata, Lily ;

de Klerk, Nicholas ;

Serralha, Michael ;

Holt, Barbara J. ;

Zhang, Guicheng ;

Loh, Richard ;

Ahlstedt, Staffan ;

Sly, Peter D. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2010, 125 (03) :653-659

[4] Sensitization to airborne environmental allergens: unresolved issues [J].

Holt, PG ;

Thomas, WR .

NATURE IMMUNOLOGY, 2005, 6 (10) :957-960

[5] Regulation of house dust mite responses by intranasally administered peptide: Transient activation of CD4(+) T cells precedes the development of tolerance in vivo [J].

Hoyne, GF ;

Askonas, BA ;

Hetzel, C ;

Thomas, WR ;

Lamb, JR .

INTERNATIONAL IMMUNOLOGY, 1996, 8 (03) :335-342

[6] Modified th2 responses at high-dose exposures to allergen - Using an occupational model [J].

Jeal, Hayley ;

Draper, Adrian ;

Harris, Jessica ;

Taylor, Anthony Newman ;

Cullinan, Paul ;

Jones, Meinir .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 174 (01) :21-25

[7] Mechanisms of immunotherapy to aeroallergens [J].

Shamji, M. H. ;

Durham, S. R. .

CLINICAL AND EXPERIMENTAL ALLERGY, 2011, 41 (09) :1235-1246

[8] Defective aeroallergen surveillance by airway mucosal dendritic cells as a determinant of risk for persistent airways hyper-responsiveness in experimental asthma [J].

Strickland, D. H. ;

Thomas, J. A. ;

Mok, D. ;

Blank, F. ;

McKenna, K. L. ;

Larcombe, A. N. ;

Sly, P. D. ;

Holt, P. G. .

MUCOSAL IMMUNOLOGY, 2012, 5 (03) :332-341

[9] Early life environmental control - Effect on symptoms, sensitization, and lung function at age 3 years [J].

Woodcock, A ;

Lowe, LA ;

Murray, CS ;

Simpson, BM ;

Pipis, SD ;

Kissen, P ;

Simpson, A ;

Custovic, A .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 170 (04) :433-439

← 1 →