The Relation of input factors and output in regional economy is complicated, this paper introduces the fuzzy system into the economic field, using the sugeon fuzzy model to construct the mapping relation between production factors and economic output. Taking China as an example, firstly, selects capital asserts and human capital as economic iuput factors, GDP as economic output, and then establishes the system structure, finally determines the final parameters by BP algorithm. The case study shows that the fuzzy model has better performance than regression, and the fuzzy if-then rules can give valuable economic decision-making macroscopically.