Atrophy and decreased activation of fronto-parietal attention areas contribute to higher visual dysfunction in posterior cortical atrophy

被引：14

作者：

Feldmann, Adam ^{[1
]}

Trauninger, Anita ^{[1
]}

Toth, Lilla ^{[2
]}

Kotek, Gyula ^{[2
]}

Kosztolanyi, Peter ^{[1
]}

Illes, Eniko ^{[1
]}

Pfund, Zoltan ^{[1
]}

Komoly, Samuel ^{[1
]}

Nagy, Ferenc ^{[1
]}

Illes, Zsolt ^{[1
]}

机构：

[1] Univ Pecs, Dept Neurol, H-7623 Pecs, Hungary

[2] Univ Kaposvar, Inst Diagnost Imaging & Radiat Oncol, H-7400 Kaposvar, Hungary

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 2008年 / 164卷 / 02期

关键词：

Atrophy; Functional magnetic resonance (fMRI); Voxel-based morphometry; Dementia; Alzheimer's disease;

D O I：

10.1016/j.pscychresns.2008.01.006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Voxel-based morphometry and functional magnetic resonance imaging demonstrated severe atrophy and decreased activation of visual attention areas and occipital lobes in a patient with early posterior cortical atrophy compared with healthy controls and patients with early Alzheimer's disease. Our complex approach indicates that structures responsible for attention can be damaged early in posterior cortical atrophy and may contribute to the characteristic decline in higher visual functions. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

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收藏

页码：178 / 184

页数：7

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