Separation of no-carrier-added 203Pb, a surrogate radioisotope, from proton irradiated natTl2CO3 target using calcium alginate hydrogel beads

被引：3
作者：
Sarkar, Kangkana [2 ]
Lahiri, Susanta [1 ]
Sen, Kamalika [2 ]
机构：
[1] Saha Inst Nucl Phys, 1-AF Bidhannagar, Kolkata 700064, India
[2] Univ Calcutta, Dept Chem, 92 APC Rd, Kolkata 700009, W Bengal, India
来源：
RADIOCHIMICA ACTA | 2016年 / 104卷 / 12期
关键词：
Pb-203; no-carrier-added; calcium alginate; iron doped calcium alginate; ION-EXCHANGE CHROMATOGRAPHY; TRACER PACKET TECHNIQUE; NUCLEAR-REACTIONS; NATURAL THALLIUM; TL-201; RADIONUCLIDES; MELANOMA; LEAD; RADIATION; ISOTOPES;
D O I：
10.1515/ract-2016-2622
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Pb-203 is a promising radioisotope in the field of medical science as an imaging surrogate of Pb-212. In the present investigation Pb-203 was produced by proton irradiation of natural Tl2CO3 target and was separated from the bulk Tl target using calcium alginate (CA) hydrogel beads with a high separation factor (3.8 x 10(4) at 10(-3) M HNO3). During the separation process Pb-203 was encapsulated in CA beads and desorption of the radioisotope could only be achieved in 1M HNO3. Possibility of Tl uptake was also checked in Fe doped CA (Fe-CA) beads after oxidation of Tl(I) to Tl(III) by sodium bismuthate. No significant uptake of Tl(III) was noticed in the Fe-CA beads. The matrix is therefore suitable for isolation of Pb-203 from the target as well as its storage in the bead for therapeutic as well as diagnostic purpose.
引用
收藏
页码：891 / 896
页数：6
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