Hepatopulmonary syndrome: Use of extracorporeal life support for life-threatening hypoxia following liver transplantation

被引:39
作者
Fleming, Geoffrey M. [1 ]
Cornell, Timothy T. [2 ]
Welling, Theodore H. [2 ]
Magee, John C. [2 ]
Annich, Gail M. [2 ]
机构
[1] Monroe Carell Childrens Hosp, Nashville, TN USA
[2] Univ Michigan, Ann Arbor, MI 48109 USA
关键词
D O I
10.1002/lt.21477
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Hepatopulmonary syndrome is an uncommon complication of nonacute liver failure, and in rare cases, hypoxia may be the presenting sign of liver dysfunction. The condition, once thought to be a contraindication, is improved in most cases by transplantation. There is a significant risk of postoperative, hypoxia-related morbidity and mortality in patients with hepatopulmonary syndrome. We present a case of life-threatening hypoxia following liver transplantation for liver failure and associated hepatopulmonary syndrome, with successful management using extracorporeal membrane oxygenation.
引用
收藏
页码:966 / 970
页数:5
相关论文
共 25 条
[1]   PULMONARY ARTERIOVENOUS SHUNTING IN CHILDREN WITH LIVER-DISEASE [J].
BARBE, T ;
LOSAY, J ;
GRIMON, G ;
DEVICTOR, D ;
SARDET, A ;
GAUTHIER, F ;
HOUSSIN, D ;
BERNARD, O .
JOURNAL OF PEDIATRICS, 1995, 126 (04) :571-579
[2]   Current status of paediatric heart, lung, and heart-lung transplantation [J].
Burch, M ;
Aurora, P .
ARCHIVES OF DISEASE IN CHILDHOOD, 2004, 89 (04) :386-389
[3]   Hepatopulmonary syndrome - A pulmonary vascular complication of liver disease [J].
Castro, M ;
Krowka, MJ .
CLINICS IN CHEST MEDICINE, 1996, 17 (01) :35-+
[4]   Long-term outcome of living related river transplantation for patients with intrapulmonary shunting and strategy for complications [J].
Egawa, H ;
Kasahara, M ;
Inomata, Y ;
Uemoto, S ;
Asonuma, K ;
Fujita, S ;
Kiuchi, T ;
Hayashi, M ;
Yonemura, T ;
Yoshibayashi, M ;
Adachi, Y ;
Shapiro, JAM ;
Tanaka, K .
TRANSPLANTATION, 1999, 67 (05) :712-717
[5]  
FLEMING GM, 2007, 18 ANN ELSO C SEPT
[6]   Expanded efficacy and indication of extracorporeal membrane oxygenation for preoperative pulmonary bleeding on pediatric cadaveric orthotopic liver transplantation [J].
Fujita, S ;
Hemming, AW ;
Fujikawa, T ;
Reed, AI ;
Howard, RJ ;
Langham, MR ;
Kays, DW ;
Froelich, MA ;
Kushihata, F ;
Watanabe, J .
TRANSPLANTATION, 2005, 79 (11) :1637-1637
[7]  
Goldstein Brahm, 2005, Pediatr Crit Care Med, V6, P2
[8]   ORTHOTOPIC LIVER-TRANSPLANTATION IN CHILDREN WITH CHRONIC LIVER-DISEASE AND SEVERE HYPOXEMIA [J].
HOBEIKA, J ;
HOUSSIN, D ;
BERNARD, O ;
DEVICTOR, D ;
GRIMON, G ;
CHAPUIS, Y .
TRANSPLANTATION, 1994, 57 (02) :224-228
[9]   FREQUENCY AND SIGNIFICANCE OF INTRAPULMONARY RIGHT-TO-LEFT SHUNTING IN END-STAGE HEPATIC-DISEASE [J].
HOPKINS, WE ;
WAGGONER, AD ;
BARZILAI, B .
AMERICAN JOURNAL OF CARDIOLOGY, 1992, 70 (04) :516-519
[10]  
JENG LBB, 1994, TRANSPLANT P, V26, P2237