Intranasal transmission of hepatitis C virus: Virological and clinical evidence

被引：61

作者：

Aaron, Sagiv ^{[2
]}

McMahon, James M. ^{[1
,3
]}

Milano, Danielle ^{[4
]}

Torres, Leilani ^{[3
]}

Clatts, Michael ^{[7
]}

Tortu, Stephanie ^{[6
]}

Mildvan, Donna ^{[5
]}

Simm, Malgorzata ^{[2
]}

机构：

[1] Univ Rochester, Sch Nursing, Med Ctr, Rochester, NY 14642 USA

[2] Columbia Univ, Div Mol Virol, St Lukes Roosevelt Inst Hlth Sci, New York, NY USA

[3] Natl Dev & Res Inst, New York, NY USA

[4] Boriken Neighborhood Hlth Ctr, New York, NY USA

[5] Beth Israel Deaconess Med Ctr, Div Infect Dis, New York, NY 10003 USA

[6] Louisiana State Univ, Sch Publ Hlth, New Orleans, LA USA

[7] Univ Puerto Rico, Sch Publ Hlth, Ctr Global Hlth Res, San Juan, PR 00936 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2008年 / 47卷 / 07期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1086/591699

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Intranasal transmission of hepatitis C virus (HCV) via contaminated drug-sniffing implements is a potential but unconfirmed source of viral infection. We demonstrate the virological plausibility of intranasal transmission by confirming that blood and HCV RNA are present in the nasal secretions and drug-sniffing implements of HCV-infected intranasal drug users recruited from a community health clinic in New York City.

引用

页码：931 / 934

页数：4

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