In vitro activity of telavancin against resistant gram-positive bacteria

被引：76

作者：

Krause, Kevin M. ^{[1
]}

Renelli, Marika ^{[1
]}

Difuntorum, Stacey ^{[1
]}

Wu, Terry X. ^{[1
]}

Debabov, Dmitri V. ^{[1
]}

Benton, Bret M. ^{[1
]}

机构：

[1] Theravance Inc, San Francisco, CA 94080 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 07期

关键词：

D O I：

10.1128/AAC.01398-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activity of telavancin was tested against 743 predominantly antimicrobial-resistant, gram-positive isolates. Telavancin was highly active against methicillin-resistant staphylococci (MIC90, 0.5 to 1 mu g/ml), streptococci (all MICs, <= 0.12 mu g/ml), and VanB-type enterococci (all MICs, <= 2 mu g/ml). Time-kill studies demonstrated the potent bactericidal activity of telavancin.

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页码：2647 / 2652

页数：6

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