Why proteomics is not the new genomics and the future of mass spectrometry in cell biology

被引：22

作者：

Sidoli, Simone ^{[1
]}

Kulej, Katarzyna ^{[1
,2
]}

Garcia, Benjamin A. ^{[1
]}

机构：

[1] Univ Penn, Perelman Sch Med, Dept Biochem & Biophys, Epigenet Program, Philadelphia, PA 19104 USA

[2] Childrens Hosp Philadelphia, Div Canc Pathobiol, Philadelphia, PA 19104 USA

来源：

JOURNAL OF CELL BIOLOGY | 2017年 / 216卷 / 01期

基金：

美国国家卫生研究院;

关键词：

STEM-CELLS; IN-VIVO; DRAFT;

D O I：

10.1083/jcb.201612010

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Mass spectrometry (MS) is an essential part of the cell biologist's proteomics toolkit, allowing analyses at molecular and system-wide scales. However, proteomics still lag behind genomics in popularity and ease of use. We discuss key differences between MS-based-omics and other booming-omics technologies and highlight what we view as the future of MS and its role in our increasingly deep understanding of cell biology.

引用

页码：21 / 24

页数：4

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