The role of MCM/P1 proteins in the licensing of DNA replication

被引：145
作者：
Chong, JPJ
Thommes, P
Blow, JJ
机构：
[1] ICRF Clare Hall Laboratories, Potters Bar, Herts, EN6 3LD, Blanche Lane
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 03期
关键词：
D O I：
10.1016/S0968-0004(96)10013-X
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The DNA replication licensing system ensures that eukaryotic chromosomes replicate precisely once per cell cycle. A central component of the licensing system, RLF-M, has recently been shown to consist of a complex of Mcm/P1 proteins. This result allows us to integrate data about the MCM/P1 family obtained in different eukaryotes, ranging from yeast to man, into a general picture of the way that chromosome replication is controlled.
引用
收藏
页码：102 / 106
页数：5
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