Synthesis of 2,5-di(hydroxyalkyl)-1,3-thiazoles

被引：3

作者：

Sinenko, V. O. ^{[1
]}

Slivchuk, S. R. ^{[1
]}

Bal'on, Ya. G. ^{[2
]}

Brovarets, V. S. ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Inst Bioorgan Chem & Petrochem, UA-02660 Kiev, Ukraine

[2] Natl Acad Med Sci, Komisarenko Inst Endocrinol & Metab, Kiev, Ukraine

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2015年 / 85卷 / 08期

关键词：

1,3-thiazole; n-butyllithium; electrophile; diol; SUBSTITUTED THIAZOLIDONES; 4-THIAZOLIDONE; DERIVATIVES; INHIBITORS; RING;

D O I：

10.1134/S1070363215080113

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A general approach towards synthesis of 2(5)-hydroxyalkyl-substituted 1,3-thiazole derivatives has been proposed. The method includes lithiation of 1,3-thiazole ring followed by reacting the formed thiazole lithium derivatives with electrophiles.

引用

页码：1855 / 1861

页数：7

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