Iridium/Chiral Diene-Catalyzed Enantioselective (3+2) Annulation of Aromatic Ketimines with 1,3-Enynes via C-H Activation

被引：40
作者：
Nagamoto, Midori [1 ]
Sakamoto, Kana [2 ]
Nishimura, Takahiro [2 ]
机构：
[1] Kyoto Univ, Dept Chem, Grad Sch Sci, Sakyo Ku, Kyoto 6068502, Japan
[2] Osaka City Univ, Dept Chem, Grad Sch Sci, Osaka 5588585, Japan
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 04期
关键词：
Iridium; C-H activation; enynes; annulation; chiral dienes; N-SULFONYL KETIMINES; BOND ACTIVATION; INDENE FRAMEWORKS; ACYL KETIMINES; ALKYNES; LIGANDS; FUNCTIONALIZATION; 1,3-DIENES; COMPLEXES; KETONES;
D O I：
10.1002/adsc.201701378
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
An iridium/chiral diene complex efficiently catalyzed enantioselective (3+2) annulation between 1,3-enynes and cyclic N-acyl ketimines generated insitu from 3-aryl-3-hydroxyisoindoin-1-ones. The reaction gave the corresponding aminoindane derivatives in high yields with high regio-, diastereo-, and enantioselectivity.
引用
收藏
页码：791 / 795
页数：5
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