Iridium/Chiral Diene-Catalyzed Enantioselective (3+2) Annulation of Aromatic Ketimines with 1,3-Enynes via C-H Activation

被引：40

作者：

Nagamoto, Midori ^{[1
]}

Sakamoto, Kana ^{[2
]}

Nishimura, Takahiro ^{[2
]}

机构：

[1] Kyoto Univ, Dept Chem, Grad Sch Sci, Sakyo Ku, Kyoto 6068502, Japan

[2] Osaka City Univ, Dept Chem, Grad Sch Sci, Osaka 5588585, Japan

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 04期

关键词：

Iridium; C-H activation; enynes; annulation; chiral dienes; N-SULFONYL KETIMINES; BOND ACTIVATION; INDENE FRAMEWORKS; ACYL KETIMINES; ALKYNES; LIGANDS; FUNCTIONALIZATION; 1,3-DIENES; COMPLEXES; KETONES;

D O I：

10.1002/adsc.201701378

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

An iridium/chiral diene complex efficiently catalyzed enantioselective (3+2) annulation between 1,3-enynes and cyclic N-acyl ketimines generated insitu from 3-aryl-3-hydroxyisoindoin-1-ones. The reaction gave the corresponding aminoindane derivatives in high yields with high regio-, diastereo-, and enantioselectivity.

引用

页码：791 / 795

页数：5

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