Clinically significant anti M antibodies - A report of two cases

被引：6

作者：

Kaur, Gagandeep ^{[1
]}

Basu, Sabita ^{[1
]}

Kaur, Paramjit ^{[1
]}

Kaur, Ravneet ^{[1
]}

机构：

[1] Govt Med Coll & Hosp, Dept Transfus Med, Chandigarh 160032, India

来源：

TRANSFUSION AND APHERESIS SCIENCE | 2012年 / 47卷 / 03期

关键词：

Anti-M; Naturally occurring antibody; Pretransfusion testing;

D O I：

10.1016/j.transci.2012.07.023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: Most anti-M antibodies are not active at 37 degrees C and are thus of no clinical significance. Occasionally these antibodies have a wide thermal range and can lead to hemolytic transfusion reactions or hemolytic disease of the new born. Patient and methods: We describe two cases of anti-M antibodies, both of which were clinically significant. Results: The first case was detected due to crossmatch incompatibility and the second presented as a blood group discrepancy. Conclusion: When the antibody is active at 37 degrees C, M antigen negative red cell units should be issued. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：259 / 261

页数：3

共 19 条

[1] A CLINICALLY SIGNIFICANT ANTI-N IN A PATIENT WHOSE RED-CELLS WERE NEGATIVE FOR N-ANTIGEN AND U-ANTIGEN [J].

BALLAS, SK ;

DIGNAM, C ;

HARRIS, M ;

MARCOLINA, MJ .

TRANSFUSION, 1985, 25 (04) :377-380

[2]

BEAL RW, 1979, CLIN OBSTET GYNAECOL, V6, P493

[3]

Brecher ME, 2008, TECHNICAL MANUAL, P911

[4] AN AUTO-ANTI-M CAUSING HEMOLYSIS INVITRO [J].

COMBS, MR ;

OROURKE, MM ;

ISSITT, PD ;

TELEN, MJ .

TRANSFUSION, 1991, 31 (08) :756-758

[5]

Daniels G., 2002, HUMAN BLOOD GROUPS, P146

[6] Blood groups: the past 50 years [J].

Daniels, Geoff ;

Reid, Marion E. .

TRANSFUSION, 2010, 50 (02) :281-289

[7] HEMOLYTIC-DISEASE OF THE NEWBORN DUE TO ANTI-M [J].

DUGUID, JKM ;

BROMILOW, IM ;

ENTWISTLE, GD ;

WILKINSON, R .

VOX SANGUINIS, 1995, 68 (03) :195-196

[8]

FURUKAWA K, 1993, EXP CLIN IMMUNOGENET, V10, P161

[9]

Hasse, 1955, VOX SANG, V5, P34

[10] Naturally occurring anti M complicating ABO grouping [J].

Khalid, Safoorah ;

Dantes, Roelyn ;

Varghese, Sunu ;

Al Hakawati, Imadeddin .

INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2011, 54 (01) :170-172

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