Gene therapy for cancer

被引:0
|
作者
Rojas-Martínez, A [1 ]
Martínez-Dávila, IA [1 ]
Hernández-García, A [1 ]
Aguilar-Córdova, E [1 ]
Barrera-Saldaña, HA [1 ]
机构
[1] Univ Autonoma Nuevo Leon, Fac Med, Dept Bioquim, Unidad Labs Ingn & Expres Genet,Lab Genet Mol, Monterrey 64460, Nuevo Leon, Mexico
来源
REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION | 2002年 / 54卷 / 01期
关键词
gene therapy; cancer; transduction; conditioned toxicity; immunotherapy;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gene therapy is a new, modality of treatment in which a gene is used to modify or add new biochemical properties to a patient's target cells with therapeutics purposes. Currently, this experimental therapy is under intensive development as an alternative to treat cancer, because it is possible that this therapy may generate a higher antineoplastic activity, more tissue selectivity and less contralateral effects than conventional therapy. After a decade of preclinical and clinical assays, still there are several obstacles that impose limits to the antineoplasic efficacy of this therapy. However, with the advances in molecular biology and related fields, there is a promise to improve, expand and strength the powerful antineoplastic arsenal of gene therapy.
引用
收藏
页码:57 / 67
页数:11
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