Dual-channel fluorescent probe based on bisphenol A-rhodamine for Zn2+ and Hg2+ through different signaling mechanisms and its bioimaging studies

被引：59

作者：

Erdemir, Serkan ^{[1
]}

Yuksekogul, Mesut ^{[1
]}

Karakurt, Serdar ^{[2
]}

Kocyigit, Ozcan ^{[1
]}

机构：

[1] Selcuk Univ, Fac Sci, Dept Chem, TR-42031 Konya, Turkey

[2] Selcuk Univ, Fac Sci, Dept Biochem, TR-42031 Konya, Turkey

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 2017年 / 241卷

关键词：

Bisphenol A; Rhodamine; Turn on; Zinc; Mercury; MOLECULAR LOGIC GATE; COLORIMETRIC SENSOR; LIVING CELLS; CHEMOSENSOR; AL3+; ION; CONJUGATE; ZINC; RECOGNITION; CADMIUM;

D O I：

10.1016/j.snb.2016.10.082

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel dual channel probe based on bisphenol A-rhodamine (BAR) was successfully designed and synthesized with high selectivity and sensitivity to Zn2+ and Hg2+ ions. BAR exhibited an effectively selective and sensitive recognition toward Zn2+ and Hg2+ ions through two different mechanisms (i.e. ESIPT and FRET) in pure MeCN and MeCN-H2O (v/v = 8/2, 5 mM, HEPES, pH 7.0) over other cations. The complexation properties of BAR with Zn2+ and Hg2+ ions were examined by H-1 NMR, C-13 NMR and FTIR experiments. The detection limits for Zn2+ and Hg2+ were 2.21 and 2.16 mu M, respectively. Furthermore, possible utilization of BAR as bio-imaging fluorescent probe to detect Hg2+ in human prostate cancer cell lines was ;also observed by Fluorescent Cell Imager. (C) 2016 Elsevier B.V. All rights reserved.

引用

页码：230 / 238

页数：9

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