Good Syndrome, a rare disease that physicians cannot afford to overlook; Case report and review of literature

Good syndrome (thymoma with immunodeficiency) is a rare cause of immunodeficiency.(1) There is a combined B and T cell immunodeficiency with hypogammaglobulinemia, reversal of the CD4/CD8 ratio and reduced or absent B cells causing an increased susceptibility to bacterial, viral and fungal infections. It is classified as a primary immunodeficiency,(2) and patients usually present with recurrent infections or a mediastinal mass.(3) The infrequency with which it is encountered makes Good syndrome a diagnostic challenge.