Oxazolidinones as chiral auxiliaries in asymmetric aldol reactions applied to total synthesis

被引：165

作者：

Heravi, Majid M. ^{[1
]}

Zadsirjan, Vahideh ^{[1
]}

机构：

[1] Alzahra Univ, Sch Sci, Dept Chem, Tehran, Iran

来源：

TETRAHEDRON-ASYMMETRY | 2013年 / 24卷 / 19期

关键词：

STEREOSELECTIVE TOTAL-SYNTHESIS; CYTOTOXIC 35-MEMBERED CYCLODEPSIPEPTIDES; CYANOBACTERIUM LYNGBYA-MAJUSCULA; ICHTHYOTOXIC CYCLIC LIPOPEPTIDE; DINOFLAGELLATE AMPHIDINIUM SP; ALDER CYCLOADDITION REACTIONS; DIARRHETIC SHELLFISH TOXINS; SPONGE DYSIDEA-ARENARIA; MICROSCLERODERMINS F-I; FORMAL TOTAL SYNTHESIS;

D O I：

10.1016/j.tetasy.2013.08.011

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Asymmetric aldol reactions of oxazolidinones as chiral auxiliaries have been achieved and attracted significant consideration as one of the most powerful synthetic tools for the carbon-carbon bond-forming reactions. The methodology has been highly successful in the stereoselective construction of a number of natural products, antibiotics, and other medicinally important compounds. The present review is focused on the utility and versatility of oxazolidinones (Evans chiral auxiliaries) in the asymmetric aldol condensations for the total synthesis of natural products and complex targets. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：1149 / 1188

页数：40

共 196 条

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