Ultrastructural study of an apatite layer formed by a biomimetic process and its bonding to bone

被引：84

作者：

Tanahashi, M

Kokubo, T

Nakamura, T

Katsura, Y

Nagano, M

机构：

[1] KYOTO UNIV,FAC ENGN,DIV MAT CHEM,SAKYO KU,KYOTO 606,JAPAN

[2] KYOTO UNIV,BIOMED ENGN RES CTR,SAKYO KU,KYOTO 606,JAPAN

[3] KYOTO UNIV,FAC MED,SAKYO KU,KYOTO 606,JAPAN

来源：

BIOMATERIALS | 1996年 / 17卷 / 01期

关键词：

bone-like apatite; biomimetic process; TEM; implantation;

D O I：

10.1016/0142-9612(96)80754-X

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A dense and uniform apatite layer about 20 mu m thick was formed on a poly(ether sulphone) (PESF) substrate treated with glow discharge in O-2 gas by a biomimetic process. The apatite-polymer composite obtained was implanted into a rabbit tibia and the structure of the PESF-apatite-bone interface was observed under a scanning and a transmission electron microscope 8 weeks after implantation. The apatite layer formed by the biomimetic process was confirmed to consist of small crystals of apatite with a structure similar to that of apatite in bone. The apatite layer remained on the substrate in the body, and bonded to the apatite in the bone directly. This type of apatite-organic polymer composite expected to be useful as bone-repairing material.

引用

页码：47 / 51

页数：5

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