The therapeutic potential of angiotensin-(1-7) as a novel renin-angiotensin system mediator

被引：1
作者：
Silva, ACE
Pinheiro, SVB
Pereira, RM
Ferreira, AJ
Santos, RAS
机构：
[1] Univ Fed Minas Gerais, Fac Med, Dept Pediat, BR-30130100 Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, Inst Ciencias Biol, Dept Mofol, BR-31270901 Belo Horizonte, MG, Brazil
[3] Univ Fed Minas Gerais, Dept Fisiol & Biofis, Lab Hipertensao, BR-31270901 Belo Horizonte, MG, Brazil
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2006年 / 6卷 / 05期
关键词：
Angiotensin-(1-7); Mas receptor; Angiotensin-converting enzyme 2; Angiotensin II; AVE; 0991; Angiotensin antagonists; Renin-Angiotensin System;
D O I：
暂无
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
In this review, we show Angiotensin-(1-7) as a novel Renin Angiotensin System mediator that antagonizes cardiovascular and proliferative effects of Angiotensin II and exerts complex renal actions. We also speculate the possibility of new drugs for the treatment of cardiovascular, genitourinary and hepatic diseases by interfering with ACE2-Angiotensin-(1-7)-Mas axis.
引用
收藏
页码：603 / 609
页数：7
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