Plasma-Generated Poly(allyl alcohol) Antifouling Coatings for Cellular Attachment
被引:6
作者:
Watkins, Lucy M.
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Univ York, Dept Chem, Heslington Rd, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Chem, Heslington Rd, York YO10 5DD, N Yorkshire, England
Watkins, Lucy M.
[1
]
Lee, Adam F.
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Aston Univ, European Bioenergy Res Inst, Birmingham B4 7ET, W Midlands, EnglandUniv York, Dept Chem, Heslington Rd, York YO10 5DD, N Yorkshire, England
Lee, Adam F.
[3
]
Moir, James W. B.
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Univ York, Dept Biol, Heslington Rd, York YO10 5DD, N Yorkshire, EnglandUniv York, Dept Chem, Heslington Rd, York YO10 5DD, N Yorkshire, England
Moir, James W. B.
[2
]
Wilson, Karen
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Aston Univ, European Bioenergy Res Inst, Birmingham B4 7ET, W Midlands, EnglandUniv York, Dept Chem, Heslington Rd, York YO10 5DD, N Yorkshire, England
Wilson, Karen
[3
]
机构:
[1] Univ York, Dept Chem, Heslington Rd, York YO10 5DD, N Yorkshire, England
[2] Univ York, Dept Biol, Heslington Rd, York YO10 5DD, N Yorkshire, England
[3] Aston Univ, European Bioenergy Res Inst, Birmingham B4 7ET, W Midlands, England
Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energy efficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.