Plasma-Generated Poly(allyl alcohol) Antifouling Coatings for Cellular Attachment

被引:6
作者
Watkins, Lucy M. [1 ]
Lee, Adam F. [3 ]
Moir, James W. B. [2 ]
Wilson, Karen [3 ]
机构
[1] Univ York, Dept Chem, Heslington Rd, York YO10 5DD, N Yorkshire, England
[2] Univ York, Dept Biol, Heslington Rd, York YO10 5DD, N Yorkshire, England
[3] Aston Univ, European Bioenergy Res Inst, Birmingham B4 7ET, W Midlands, England
来源
ACS BIOMATERIALS SCIENCE & ENGINEERING | 2017年 / 3卷 / 01期
关键词
plasma; polyurethane; XPS; biofilm; polymerization; fibroblast; ALLYL ALCOHOL; ACRYLIC-ACID; SURFACE CHARACTERIZATION; POLYSTYRENE SURFACES; HUMAN KERATINOCYTES; BACTERIAL ADHESION; FILMS; POLYMERIZATION; POLYURETHANE; POLYMERS;
D O I
10.1021/acsbiomaterials.6b00705
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energy efficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.
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页码:88 / 94
页数:7
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