Reactive sulfur species (RSS): persulfides, polysulfides, potential, and problems

被引：122

作者：

Lau, Nathanael ^{[1
]}

Pluth, Michael D. ^{[1
]}

机构：

[1] Univ Oregon, Inst Mat Sci, Inst Mol Biol, Dept Chem & Biochem, Eugene, OR 97403 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2019年 / 49卷

关键词：

HYDROGEN-SULFIDE; ALKALI POLYSULFIDES; S-NITROSOTHIOLS; RADICAL-ANIONS; NITRIC-OXIDE; SOLID-STATE; NO; H2S; HSNO; PERTHIONITRITE;

D O I：

10.1016/j.cbpa.2018.08.012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sulfur is a crucial element in biology due to its unique properties and wide range of accessible oxidation states. This reactivity gives rise to the generation of reactive sulfur species (RSS), which have emerged as a diverse class of small molecules and functional groups with important roles in chemical biology and bioinorganic chemistry. In this review, we focus on basic properties of simple RSS, highlight recent insights into the interconnectivity of RSS with reactive nitrogen species, and discuss recent advances in methods for RSS detection and measurement. Finally, we highlight key reactivity considerations that must be taken into account when working with RSS and interpreting the outcomes of labeling methods for RSS and related species.

引用

页码：1 / 8

页数：8

共 59 条

[11] Inorganic sulfur-nitrogen compounds: from gunpowder chemistry to the forefront of biological signaling [J].

Cortese-Krott, Miriam M. ;

Butler, Anthony R. ;

Woollins, J. Derek ;

Feelisch, Martin .

DALTON TRANSACTIONS, 2016, 45 (14) :5908-5919

[12] Key bioactive reaction products of the NO/H2S interaction are S/N-hybrid species, polysulfides, and nitroxyl [J].

Cortese-Krott, Miriam M. ;

Kuhnle, Gunter G. C. ;

Dyson, Alex ;

Fernandez, Bernadette O. ;

Grman, Marian ;

DuMond, Jenna F. ;

Barrow, Mark P. ;

McLeod, George ;

Nakagawa, Hidehiko ;

Ondrias, Karol ;

Nagy, Peter ;

King, S. Bruce ;

Saavedra, Joseph E. ;

Keefer, Larry K. ;

Singer, Mervyn ;

Kelm, Malte ;

Butler, Anthony R. ;

Feelisch, Martin .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (34) :E4651-E4660

[13] Nitrosopersulfide (SSNO-) accounts for sustained NO bioactivity of S-nitrosothiols following reaction with sulfide [J].

Cortese-Krott, Miriam M. ;

Fernandez, Bernadette O. ;

Santos, Jose L. T. ;

Mergia, Evanthia ;

Grman, Marian ;

Nagy, Peter ;

Kelm, Malte ;

Butler, Anthony ;

Feelisch, Martin .

REDOX BIOLOGY, 2014, 2 :234-244

[14] A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems [J].

Doka, Eva ;

Pader, Irina ;

Biro, Adrienn ;

Johansson, Katarina ;

Cheng, Qing ;

Ballago, Krisztina ;

Prigge, Justin R. ;

Pastor-Flores, Daniel ;

Dick, Tobias P. ;

Schmidt, Edward E. ;

Arner, Elias S. J. ;

Nagy, Peter .

SCIENCE ADVANCES, 2016, 2 (01)

[15] Chemical Biology of H2S Signaling through Persulfidation [J].

Filipovic, Milos R. ;

Zivanovic, Jasmina ;

Alvarez, Beatriz ;

Banerjee, Ruma .

CHEMICAL REVIEWS, 2018, 118 (03) :377-461

[16] Chemical Characterization of the Smallest S-Nitrosothiol, HSNO; Cellular Cross-talk of H2S and S-Nitrosothiols [J].

Filipovic, Milos R. ;

Miljkovic, Jan Lj ;

Nauser, Thomas ;

Royzen, Maksim ;

Klos, Katharina ;

Shubina, Tatyana ;

Koppenol, Willem H. ;

Lippard, Stephen J. ;

Ivanovic-Burmazovic, Ivana .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (29) :12016-12027

[17] Spectral monitoring of the formation and degradation of polysulfide ions in alkaline conditions [J].

Filpponen, Ilari ;

Guerra, Anderson ;

Hai, Abdul ;

Lucia, n A. Lucia ;

Argyropoulos, Dimitris S. .

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2006, 45 (22) :7388-7392

[18] Biological hydropersulfides and related polysulfides - a new concept and perspective in redox biology [J].

Fukuto, Jon M. ;

Ignarro, Louis J. ;

Nagy, Peter ;

Wink, David A. ;

Kevil, Christopher G. ;

Feelisch, Martin ;

Cortese-Krott, Miriam M. ;

Bianco, Christopher L. ;

Kumagai, Yoshito ;

Hobbs, Adrian J. ;

Lin, Joseph ;

Ida, Tomoaki ;

Akaike, Takaaki .

FEBS LETTERS, 2018, 592 (12) :2140-2152

[19] Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response [J].

Gao, Xing-Huang ;

Krokowski, Dawid ;

Guan, Bo-Jhih ;

Bederman, Ilya ;

Majumder, Mithu ;

Parisien, Marc ;

Diatchenko, Luda ;

Kabil, Omer ;

Willard, Belinda ;

Banerjee, Ruma ;

Wang, Benlian ;

Bebek, Gurkan ;

Evans, Charles R. ;

Fox, Paul L. ;

Gerson, Stanton L. ;

Hoppel, Charles L. ;

Liu, Ming ;

Arvan, Peter ;

Hatzoglou, Maria .

ELIFE, 2015, 4

[20] Solid-State 15N and 17O NMR Studies of S-Nitrosothiols [J].

Gao, Yin ;

Dai, Yizhe ;

Wu, Gang .

JOURNAL OF PHYSICAL CHEMISTRY B, 2017, 121 (30) :7311-7317

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