The last 100 years of sepsis

被引：111

作者：

Vincent, JL

Abraham, E

机构：

[1] Free Univ Brussels, Erasme Hosp, Dept Intens Care, B-1070 Brussels, Belgium

[2] Univ Colorado, Div Pulm Sci & Crit Care Med, Denver, CO 80202 USA

[3] Hlth Sci Ctr, Denver, CO USA

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2006年 / 173卷 / 03期

关键词：

endotoxin; cytokines; epidemiology; septic shock; immunomodulation;

D O I：

10.1164/rccm.200510-1604OE

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Over the last 100 years, huge advances have been made in the field of sepsis in terms of pathophysiology, epidemiology, diagnosis, monitoring, and therapeutics. Here, we offer our perspective of the key changes and current situation in each of these areas. Despite these changes, mortality rates remain unacceptably high and continued progress, particularly in early diagnosis and therapy, is urgently needed.

引用

页码：256 / 263

页数：8

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