Understanding the RECORDS 3 Trial and its impact on anticiagulation practice in resource poor countries

被引:1
作者
Nwagha, T. U. [1 ]
Omunakwe, H. E. [2 ]
机构
[1] Univ Nigeria, Teaching Hosp, Bleeding & Thrombosis Unit, Dept Haematol & Immunol, Ituku Ozalla, Enugu, Nigeria
[2] Braithwaite Mem Specialist Hosp, Hematol Unit, Dept Pathol, Port Harcourt, Rivers State, Nigeria
关键词
Anticoagulation practice; new anticoagulation therapy; Regulation of Coagulation in Orthopedic surgery to prevent Deep venous thrombosis and pulmonary embolism 3 trial; rivaroxaban; DEEP-VEIN THROMBOSIS; FACTOR-XA INHIBITOR; VENOUS THROMBOEMBOLISM; RIVAROXABAN BAY-59-7939; TOTAL HIP; PREVENTION; THROMBOPROPHYLAXIS; PHARMACOKINETICS; WEIGHT;
D O I
10.4103/1119-3077.180059
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Venous thromboembolism is a significant cause of mortality and morbidity in patients following major orthopaedic surgeries. The RECORDS 3 trial revolutionised anticoagulation practice especially in patients with total knee arthroplasty and challenging the strong hold of warfarin and heparin in anticoagulation practice. With all these novel agents shifting the paradigm in anticoagulation management, Cost, in accessibility and lack of awareness of the availability of the agents amongst clinicians and surgeons alike are some factors militating against the use of these agents in patients in resource poor countries.
引用
收藏
页码:695 / 699
页数:5
相关论文
共 26 条
[1]   Utilization of Oral Anticoagulation in a Teaching Hospital in Nigeria [J].
Anakwue, R. C. ;
Ocheni, S. ;
Madu, A. J. .
ANNALS OF MEDICAL AND HEALTH SCIENCES RESEARCH, 2014, 4 :286-290
[2]  
[Anonymous], 2013, Clinical trials: a practical approach
[3]  
[Anonymous], 2002, PROPHYLAXIS VENOUS T
[4]  
Deng Y, 2008, BIOSTATISTICS CLIN T
[5]   A once-daily, oral, direct Factor Xa inhibitor, rivaroxaban (BAY 59-7939), for thromboprophylaxis after total hip replacement [J].
Eriksson, Bengt I. ;
Borris, Lars C. ;
Dahl, Ola E. ;
Haas, Sylvia ;
Huisman, Menno V. ;
Kakkar, Ajay K. ;
Muehlhofer, Eva ;
Dierig, Christoph ;
Misselwitz, Frank ;
Kalebo, Peter .
CIRCULATION, 2006, 114 (22) :2374-2381
[6]   Prevention of VTE in Orthopedic Surgery Patients Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines [J].
Falck-Ytter, Yngve ;
Francis, Charles W. ;
Johanson, Norman A. ;
Curley, Catherine ;
Dahl, Ola E. ;
Schulman, Sam ;
Ortel, Thomas L. ;
Pauker, Stephen G. ;
Colwell, Clifford W., Jr. .
CHEST, 2012, 141 (02) :E278S-E325S
[7]   Physician compliance with guidelines for deep-vein thrombosis prevention in total hip and knee arthroplasty [J].
Friedman, Richard J. ;
Gallus, Alexander S. ;
Cushner, Fred D. ;
FitzGerald, Gordon ;
Anderson, Frederick A., Jr. .
CURRENT MEDICAL RESEARCH AND OPINION, 2008, 24 (01) :87-97
[8]   Prevention of venous thromboembolism [J].
Geerts, WH ;
Pineo, GF ;
Heit, JA ;
Bergqvist, D ;
Lassen, MR ;
Colwell, CW ;
Ray, JG .
CHEST, 2004, 126 (03) :338S-400S
[9]   New onset of venous thromboembolism among hospitalized patients at Brigham and Women's Hospital is caused more often by prophylaxis failure than by withholding treatment [J].
Goldhaber, SZ ;
Dunn, K ;
MacDougall, RC .
CHEST, 2000, 118 (06) :1680-1684
[10]  
Heintzelman C., 2003, The New Social Worker, V10, P4