Inhibition of tyrosinase activity on dopamine hydrochloride by kojic acid

被引：0
|
作者：
Sariri, R [1 ]
Moghimi, R [1 ]
Ranjbar, RB [1 ]
机构：
[1] Gilan Univ, Dept Biol, Rasht, Iran
来源：
ASIAN JOURNAL OF CHEMISTRY | 2006年 / 18卷 / 01期
关键词：
tyrosinase; enzyme kinetics; enzyme inhibition; polyphenol oxidase; kojic acid;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The inhibition effect of kojic acid on tyrosinase activity was studied and the rate of enzymatic reaction in presence and absence of the inhibitor was calculated. It was shown that increasing the concentration of inhibitors reduces the enzymatic reaction rate linearly. The kinetics of inhibition by kojic acid was studied and the Michaelis constants calculated. It was found that kojic acid could non-competitively inhibit the tyrosinase action on its substrate, dopamine hydrochlodride under specified conditions.
引用
收藏
页码：15 / 19
页数：5
相关论文
共 50 条
  • [11] EFFECT OF KOJIC ACID ON THE OXIDATION OF TRIHYDROXYPHENOLS BY MUSHROOM TYROSINASE
    KAHN, V
    ZAKIN, V
    JOURNAL OF FOOD BIOCHEMISTRY, 1995, 18 (06) : 427 - 443
  • [12] Stability, release, and tyrosinase inhibition behaviors of kojic acid encapsulated in the interlayer space of layered yttrium hydroxide
    Kang, Myeongjin
    Choi, Yoonjae
    Byeon, Song-Ho
    APPLIED CLAY SCIENCE, 2024, 260
  • [13] Kojic Acid Peptide: A New Compound with Anti Tyrosinase Potential
    Singh, Birendra Kumar
    Park, Seok Hoon
    Lee, Hyang-Bok
    Goo, Young-Aae
    Kim, Hyoung Shik
    Cho, Seung Hee
    Lee, Jeong Hun
    Ahn, Ghe Whan
    Kim, Jin Pyo
    Kang, Su Myoung
    Kim, Eun-Ki
    ANNALS OF DERMATOLOGY, 2016, 28 (05) : 555 - 561
  • [14] Inhibition of the catecholase activity of biomimetic dinuclear copper complexes by kojic acid
    G. Battaini
    E. Monzani
    L. Casella
    L. Santagostini
    R. Pagliarin
    JBIC Journal of Biological Inorganic Chemistry, 2000, 5 : 262 - 268
  • [15] Kojic acid-tripeptide amide as a new tyrosinase inhibitor
    Noh, Jin-Mi
    Kwak, Scon-Yeong
    Kim, Do-Hyun
    Lee, Yoon-Sik
    BIOPOLYMERS, 2007, 88 (02) : 300 - 307
  • [16] Inhibition of the catecholase activity of biomimetic dinuclear copper complexes by kojic acid
    Battaini, G
    Monzani, E
    Casella, L
    Santagostini, L
    Pagliarin, R
    JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2000, 5 (02): : 262 - 268
  • [17] Synthesis and Biological Evaluation of Kojic acid Derivatives as Tyrosinase Inhibitors
    Choi, Yeong Jin
    Rho, Ho Sik
    Baek, Heung Soo
    Hong, Yong Deog
    Joo, Yung Hyup
    Shin, Song Seok
    Kim, Ji Man
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2014, 35 (12) : 3647 - 3650
  • [18] KOJIC ACID, A TYROSINASE INHIBITOR FROM ASPERGILLUS-ALBUS
    SARUNO, R
    KATO, F
    IKENO, T
    AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1979, 43 (06): : 1337 - 1338
  • [19] KOJIC ACID, A COSMETIC SKIN WHITENING AGENT, IS A SLOW-BINDING INHIBITOR OF CATECHOLASE ACTIVITY OF TYROSINASE
    CABANES, J
    CHAZARRA, S
    GARCIACARMONA, F
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 1994, 46 (12) : 982 - 985
  • [20] EFFECT OF KOJIC ACID ON THE OXIDATION OF O-DIHYDROXYPHENOLS BY MUSHROOM TYROSINASE
    KAHN, V
    LINDNER, P
    ZAKIN, V
    JOURNAL OF FOOD BIOCHEMISTRY, 1995, 18 (04) : 253 - 271
12345