Fluorinated Graphene for Promoting Neuro-Induction of Stem Cells

被引：328

作者：

Wang, Yu ^{[3
,4
]}

Lee, Wong Cheng ^{[1
,2
]}

Manga, Kiran Kumar ^{[3
,4
]}

Ang, Priscilla Kailian ^{[3
,4
]}

Lu, Jiong ^{[3
,4
]}

Liu, Yan Peng ^{[3
,4
]}

Lim, Chwee Teck ^{[1
,2
]}

Loh, Kian Ping ^{[3
,4
]}

机构：

[1] Natl Univ Singapore, Mechanobiol Inst, Dept Bioengn, Singapore 117574, Singapore

[2] Natl Univ Singapore, Mechanobiol Inst, Dept Mech Engn, Singapore 117574, Singapore

[3] Natl Univ Singapore, Graphene Res Ctr, Singapore 117543, Singapore

[4] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

来源：

ADVANCED MATERIALS | 2012年 / 24卷 / 31期

关键词：

Graphene; Fluorination; Stem Cell; Neuro-Induction; Patterning; BONE-MARROW; DIFFERENTIATION; BIOMATERIALS; LINEAGE;

D O I：

10.1002/adma.201200846

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Surface engineering of substrates offers the possibility of controlling the physiological functions of cells at the molecular level. Fluorinated graphene promotes the differentiation of MSCs towards neuronal lineages. Cell alignment using printed polydimethylsiloxane channel arrays on fluorinated graphene further enhances the neuro-induction of MSCs even in the absence of chemical inducers.

引用

页码：4285 / +

页数：7

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