Assembly-enhanced molecular recognition of calix[6]arene

被引：10

作者：

Tian, Han-Wen ^{[1
]}

Pan, Yu-Chen ^{[1
]}

Guo, Dong-Sheng ^{[1
]}

机构：

[1] Nankai Univ, Coll Chem, State Key Lab Elementoorgan Chem, Key Lab Funct Polymer Mat,Minist Educ, Tianjin, Peoples R China

来源：

SUPRAMOLECULAR CHEMISTRY | 2018年 / 30卷 / 07期

关键词：

Molecular recognition; self-assembly; calixarene; conformation; liposome; AMPHIPHILIC CALIXARENE; METAL-CATIONS; SULFONATOCALIXARENE; CAVITY; ACETYLCHOLINE; COORDINATION; CONFORMATION; SURFACTANTS; COMPLEXES; EFFICIENT;

D O I：

10.1080/10610278.2017.1413243

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We comparatively investigated the molecular recognition of the amphiphilic derivatives of p-sulfonatocalix[n]arenes (SCnA-Rs, n=4 and 6) both in aqueous solution and at the interface of liposome. When the recognition events transfer from aqueous solution to the self-assembled interface, the binding capability of SC6A-R increases drastically, but not for SC4A-R. It originates from the conformational regulation that the complicated conformation of SC6A-R in aqueous solution was immobilized to the cone shape upon embedding SC6A-R into the liposome. The resulting cone shape is privileged to accommodate guests into its cavity. Such an assembly-enhanced molecular recognition strategy could be transferable to other macrocyclic, acyclic, artificial, and natural receptors with conformational flexibility. [GRAPHICS] .

引用

页码：562 / 567

页数：6