Structures of TMC-120A, B and C, novel isoquinoline alkaloids from Aspergillus ustus TC 1118

被引：47

作者：

Kohno, J ^{[1
]}

Hiramatsu, H ^{[1
]}

Nishio, M ^{[1
]}

Sakurai, M ^{[1
]}

Okuda, T ^{[1
]}

Komatsubara, S ^{[1
]}

机构：

[1] Tanabe Seiyaku Co Ltd, Discovery Res Lab, Toda, Saitama 3358505, Japan

来源：

TETRAHEDRON | 1999年 / 55卷 / 37期

关键词：

TMC-120A; B and C; furo[3,2-h]isoquinoline; alkaloid; Aspergillus ustus;

D O I：

10.1016/S0040-4020(99)00648-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three novel isoquinoline alkaloids, TMC-120A, B and C (1-3) have been isolated from a fermentation broth of Aspergillus ustus (Bain.) Them & Church TC 1118, a fungus isolated from rhizosphere of grass. Their structures were determined through extensive spectroscopic analyses and chemical studies. TMC-120s (1-3) are found to be the first furo[3,2-h]isoquinoline-type alkaloids isolated from natural sources, (C) 1999 Elsevier Science Ltd. Ail rights reserved.

引用

页码：11247 / 11252

页数：6