Acoustic Radiation Force Elasticity Imaging in Diagnostic Ultrasound

被引:243
作者
Doherty, Joshua R. [1 ]
Trahey, Gregg E. [1 ,2 ]
Nightingale, Kathryn R. [1 ]
Palmeri, Mark L. [1 ]
机构
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27706 USA
[2] Duke Univ, Med Ctr, Dept Radiol, Durham, NC 27710 USA
基金
美国国家卫生研究院;
关键词
LIVER STIFFNESS MEASUREMENT; TRANSIENT ELASTOGRAPHY; IN-VIVO; EX-VIVO; NONINVASIVE ASSESSMENT; VIBRO-ACOUSTOGRAPHY; HEPATIC-FIBROSIS; CRAWLING WAVES; SHEAR-MODULUS; MECHANICAL-PROPERTIES;
D O I
10.1109/TUFFC.2013.2617
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The development of ultrasound-based elasticity imaging methods has been the focus of intense research activity since the mid-1990s. In characterizing the mechanical properties of soft tissues, these techniques image an entirely new subset of tissue properties that cannot be derived with conventional ultrasound techniques. Clinically, tissue elasticity is known to be associated with pathological condition and with the ability to image these features in vivo; elasticity imaging methods may prove to be invaluable tools for the diagnosis and/or monitoring of disease. This review focuses on ultrasound-based elasticity imaging methods that generate an acoustic radiation force to induce tissue displacements. These methods can be performed noninvasively during routine exams to provide either qualitative or quantitative metrics of tissue elasticity. A brief overview of soft tissue mechanics relevant to elasticity imaging is provided, including a derivation of acoustic radiation force, and an overview of the various acoustic radiation force elasticity imaging methods.
引用
收藏
页码:685 / 701
页数:17
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