Lithium perchlorate mediated three component reaction for the preparation of primary amines

被引：10

作者：

Saidi, MR ^{[1
]}

Javanshir, S ^{[1
]}

Mojtahedi, MM ^{[1
]}

机构：

[1] Sharif Univ Technol, Dept Chem, Teheran, Iran

来源：

JOURNAL OF CHEMICAL RESEARCH-S | 1999年 / 05期

关键词：

D O I：

10.1039/a808424f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In the presence of lithium perchlorate in diethyl ether, LPDE, a three-component reaction between aldehydes, sodium hexamethyldisilazane or lithium hexamethyldisilazane, LHMDS, and different nucleophiles proceeds smoothly to afford primary amines in good yields.

引用

页码：330 / 331

页数：3

共 16 条

[1] [Anonymous], [No title captured]
[2] Arend M, 1995, ANGEW CHEM INT EDIT, V34, P2639
[3] CONN RSE, 1984, ISRAEL J CHEM, V24, P108
[4] Convenient access to primary amines by employing the Barbier-type reaction of N-(trimethylsilyl)imines derived from aromatic and aliphatic aldehydes
Gyenes, F
Bergmann, KE
Welch, JT
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (09) : 2824 - 2828
[5] BENZOTRIAZOLE-ASSISTED SYNTHESIS OF NOVEL MANNICH-BASES FROM KETONES AND DIVERSE ALDEHYDES
KATRITZKY, AR
HARRIS, PA
[J]. TETRAHEDRON, 1990, 46 (03) : 987 - 996
[6] Synthesis of primary amines via nucleophilic addition of organometallic reagents to aldimines on solid support
Katritzky, AR
Xie, LH
Zhang, GF
Griffith, M
Watson, K
Kiely, JS
[J]. TETRAHEDRON LETTERS, 1997, 38 (40) : 7011 - 7014
[7] Aldehydes vs aldimines. Unprecedented reactivity in their enolate addition reactions
Kobayashi, S
Nagayama, S
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (02) : 232 - 233
[8] KOLB M, 1983, LIEBIGS ANN CHEM, P1679
[9] NIKAN SS, 1996, J ORG CHEM, V50, P2193
[10] SYNTHESIS AND MONOAMINE-OXIDASE INHIBITORY ACTIVITIES OF ALPHA-ALLENIC AMINES INVIVO AND INVITRO - DIFFERENT ACTIVITIES OF 2 ENANTIOMERIC ALLENES
SAHLBERG, C
ROSS, SB
FAGERVALL, I
ASK, AL
CLAESSON, A
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (07) : 1036 - 1042

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