Proteomics in medicinal chemistry

被引:0
|
作者
Niwayama, S [1 ]
机构
[1] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA
关键词
proteomics; 2-D electrophoresis; high performance liquid chromatography (HPLC); isotope-coded affinity tag (ICAT); stable isotope labeling by amino acid in cell culture (SILAC); mass spectrometry (MS); drug discovery;
D O I
10.2174/138955706775476000
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Proteomics is becoming an important research area for studying protein expression patterns induced by different external stimuli. An important aspect of proteoics is to identify and quantify proteins. Many new technologies and techniques have been developed in this field and have been applied to various aspects of drug discovery.
引用
收藏
页码:241 / 246
页数:6
相关论文
共 50 条
  • [21] Rethinking Medicinal Chemistry in the Cheminformatics Age
    Oprea, Tudor I.
    Weininger, David
    JOURNAL OF MEDICINAL CHEMISTRY, 2024, 67 (20) : 17935 - 17939
  • [22] Medicinal chemistry insights into antiviral peptidomimetics
    Ding, Dang
    Xu, Shujing
    da Silva-Junior, Edeildo Ferreira
    Liu, Xinyong
    Zhan, Peng
    DRUG DISCOVERY TODAY, 2023, 28 (03) : 1 - 8
  • [23] Medicinal Chemistry Perspectives of Trioxanes and Tetraoxanes
    Kumar, N.
    Sharma, M.
    Rawat, D. S.
    CURRENT MEDICINAL CHEMISTRY, 2011, 18 (25) : 3889 - 3928
  • [24] Machine Learning in Chemoinformatics and Medicinal Chemistry
    Rodriguez-Perez, Raquel
    Miljkovic, Filip
    Bajorath, Juergen
    ANNUAL REVIEW OF BIOMEDICAL DATA SCIENCE, 2022, 5 : 43 - 65
  • [25] Public Domain Databases for Medicinal Chemistry
    Nicola, George
    Liu, Tiqing
    Gilson, Michael K.
    JOURNAL OF MEDICINAL CHEMISTRY, 2012, 55 (16) : 6987 - 7002
  • [26] MEDICINAL CHEMISTRY - PAST, PRESENT AND FUTURE
    SOUDIJN, W
    RECUEIL DES TRAVAUX CHIMIQUES DES PAYS-BAS-JOURNAL OF THE ROYAL NETHERLANDS CHEMICAL SOCIETY, 1993, 112 (02): : 43 - 50
  • [27] Saturated Heterocycles with Applications in Medicinal Chemistry
    Marson, Charles M.
    HETEROCYCLIC CHEMISTRY IN THE 21ST CENTURY: A TRIBUTE TO ALAN KATRITZKY, 2017, 121 : 13 - 33
  • [28] Coping with Polypharmacology by Computational Medicinal Chemistry
    Schneider, Gisbert
    Reker, Daniel
    Rodrigues, Tiago
    Schneider, Petra
    CHIMIA, 2014, 68 (09) : 648 - 653
  • [29] A Molecular Structure Ontology for Medicinal Chemistry
    Chui, Carmen
    Grueninger, Michael
    FORMAL ONTOLOGY IN INFORMATION SYSTEMS, 2016, 283 : 285 - 298
  • [30] Privileged structures as leads in medicinal chemistry
    Costantino, L
    Barlocco, D
    CURRENT MEDICINAL CHEMISTRY, 2006, 13 (01) : 65 - 85