Progress on Terpenoids With Biological Activities Produced by Plant Endophytic Fungi in China Between 2017 and 2019

被引:10
作者
Zhao, Yu [1 ]
Cui, Jing [2 ]
Liu, Mengyujie [2 ]
Zhao, Lei [2 ]
机构
[1] Shandong Univ, Sch Pharmaceut Sci, Jinan, Peoples R China
[2] Shandong Univ, Qilu Hosp, Dept Pharm, 107 West Wenhua Rd, Jinan 250012, Peoples R China
基金
中国国家自然科学基金;
关键词
plant endophytic fungi; terpenoids; biological activities; sesquiterpenoids; Trichoderma; Aspergillus; SESQUITERPENOIDS; MEROTERPENOIDS; HARZIANE; CULTURES; LEAVES; TAXOL;
D O I
10.1177/1934578X20937204
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Plant endophytic fungi are an important part of plant microecosystems and a natural resource for human survival and development. Various bioactive natural products produced by plant endophytic fungi show promising prospects in biopharmacy, agricultural production, and industrial fermentation. Terpenoids, the most numerous and structurally diverse natural products from endophytic fungi, possess a broad range of biological activities and huge potential for drug development. It is critically significant for ecological and economic benefits to develop their activities. This paper utilized literature analysis to summarize 200 terpenoids with biological activities that are derived from plant endophytic fungi in China between 2017 and 2019. Among them, sesquiter-penoids were the most important kind of terpenoids, and Trichoderma and Aspergillus species were main terpenoid-producing plant endophytic fungi. Furthermore, these terpenoids displayed multifarious biological activities, including antimicrobial, antipathogenic, and anti-inflammatory activities, as well as cytotoxicity, antitumor agents, and enzyme inhibition.
引用
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页数:18
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