Microwave-Assisted Formation of Peptide-Vitamin Conjugates

被引：7
作者：
El-Nachef, Claudia [1 ]
Bajaj, Kiran [1 ]
Koblick, Jacqueline [1 ]
Katritzky, Alan R. [1 ,2 ]
机构：
[1] Univ Florida, Dept Chem, Ctr Heterocycl Cpds, Gainesville, FL 32611 USA
[2] King Abdulaziz Univ, Dept Chem, Jeddah 21589, Saudi Arabia
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2012年 / 2012卷 / 23期
关键词：
Microwave chemistry; Peptides; Amino acids; Vitamins; IN-VITRO EVALUATION; ACID; DELIVERY; ENHANCEMENT; HYDROLYSIS; INHIBITORS; PATHWAY; BINDING; CELLS;
D O I：
10.1002/ejoc.201200323
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Amino acid and peptide conjugates with vitamin B3, H, E and D3 were synthesized by using microwave irradiation in good to satisfactory yields. In addition, a novel benzotriazole-activated biotin intermediate has been introduced, which could serve as an alternative biotinylation agent.
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收藏
页码：4412 / 4419
页数：8
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