Carbon nanotube based X-ray sources: Applications in pre-clinical and medical imaging

被引:18
|
作者
Lee, Yueh Z. [1 ,2 ]
Burk, Laurel [2 ]
Wang, Ko-han [1 ]
Cao, Guohua [2 ]
Lu, Jianping [3 ]
Zhou, Otto [2 ]
机构
[1] Univ N Carolina, Dept Radiol, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Phys & Astron, Chapel Hill, NC 27599 USA
[3] Univ N Carolina, Curriculum Appl Sci & Engn, Chapel Hill, NC 27599 USA
关键词
Micro-computed tomography; Pre-clinical imaging; Tomosynthesis; TOMOSYNTHESIS;
D O I
10.1016/j.nima.2010.11.053
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
Field emission offers an alternate method of electron production for Bremsstrahlung based X-ray tubes. Carbon nanotubes (CNTs) serve as very effective field emitters, allowing them to serve as electron sources for X-ray sources, with specific advantages over traditional thermionic tubes. CNT derived X-ray sources can create X-ray pulses of any duration and frequency, gate the X-ray pulse to any source and allow the placement of many sources in close proximity. We have constructed a number of micro-CT systems based on CNT X-ray sources for applications in small animal imaging, specifically focused on the imaging of the heart and lungs. This paper offers a review of the pre-clinical applications of the CNT based micro-CT that we have developed. We also discuss some of the current and potential clinical applications of the CNT X-ray sources. (c) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:S281 / S283
页数:3
相关论文
共 31 条
  • [1] Optimizing configuration parameters of a stationary digital breast tomosynthesis system based on carbon nanotube X-ray sources
    Tucker, Andrew
    Qian, Xin
    Gidcumb, Emily
    Spronk, Derrek
    Sprenger, Frank
    Kuo, Johnny
    Ng, Susan
    Lu, Jianping
    Zhou, Otto
    MEDICAL IMAGING 2012: PHYSICS OF MEDICAL IMAGING, 2012, 8313
  • [2] Carbon nanotube electron field emitters for x-ray imaging of human breast cancer
    Gidcumb, Emily
    Gao, Bo
    Shan, Jing
    Inscoe, Christy
    Lu, Jianping
    Zhou, Otto
    NANOTECHNOLOGY, 2014, 25 (24)
  • [3] Addressable flat-panel x-ray sources for medical, security and industrial applications
    Travish, Gil
    Rangel, Felix. J.
    Evans, Mark Andrew
    Hollister, Ben
    Schmiedehausen, Kristin
    ADVANCES IN X-RAY/EUV OPTICS AND COMPONENTS VII, 2012, 8502
  • [4] A multi-beam x-ray imaging system based on carbon nanotube field emitters - art. no. 614204
    Zhang, J.
    Yang, G.
    Lee, Y. Z.
    Cheng, Y.
    Gao, B.
    Qiu, Q.
    Lu, J. P.
    Zhou, O.
    Medical Imaging 2006: Physics of Medical Imaging, Pts 1-3, 2006, 6142 : 14204 - 14204
  • [5] RECENT ADVANCES AND TRENDS IN MEDICAL X-RAY AND MOLECULAR IMAGING
    Mattsson, Soren
    MEDICAL PHYSICS IN THE BALTIC STATES: PROCEEDINGS OF THE 7TH INTERNATIONAL CONFERENCE ON MEDICAL PHYSICS, 2009, : 6 - 10
  • [6] Stationary Multi X-ray Source System with Carbon Nanotube Emitters for Digital Tomosynthesis
    Park, Junyoung
    Gupta, Amar Prasad
    Kim, Wooseob
    Lim, Jongmin
    Yeo, Seungjun
    Kim, Dongkeun
    Jeong, Changwon
    Yoon, Kwon-Ha
    Cho, Seungryong
    Ahn, Jeung Sun
    Mativenga, Mallory
    Ryu, Jehwang
    MEDICAL IMAGING 2021: PHYSICS OF MEDICAL IMAGING, 2021, 11595
  • [7] Laser-wakefield accelerators as hard x-ray sources for 3D medical imaging of human bone
    Cole, J. M.
    Wood, J. C.
    Lopes, N. C.
    Poder, K.
    Abel, R. L.
    Alatabi, S.
    Bryant, J. S. J.
    Jin, A.
    Kneip, S.
    Mecseki, K.
    Symes, D. R.
    Mangles, S. P. D.
    Najmudin, Z.
    SCIENTIFIC REPORTS, 2015, 5
  • [8] MTF simulation of a-Se x-ray detector using ARTEMIS for breast imaging applications
    Cheng, Yu-Han
    Wang, Yu-Wen
    Lin, Ja-An
    Fang, Yuan
    2018 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE PROCEEDINGS (NSS/MIC), 2018,
  • [9] A cadaveric breast cancer tissue phantom for phase-contrast X-ray imaging applications
    Rounds, Cody C.
    Li, Chengyue
    Zhou, Wei
    Tichauer, Kenneth M.
    Brankov, Jovan G.
    ANIMAL MODELS AND EXPERIMENTAL MEDICINE, 2023, 6 (05) : 427 - 432
  • [10] Development of a digital panoramic X-ray imaging system of adaptive image layers for dental applications
    Choi, S. I.
    Park, Y. O.
    Cho, H. S.
    Oh, J. E.
    Cho, H. M.
    Hong, D. K.
    Lee, M. S.
    Yang, Y. J.
    Je, U. K.
    Kim, D. S.
    Lee, H. K.
    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2011, 652 (01) : 767 - 770