Regular consumption of green tea improves pulse pressure and induces regression of left ventricular hypertrophy in hypertensive patients

被引:10
作者
Al-Shafei, Ahmad I. M. [1 ,2 ,3 ]
El-Gendy, Ola A. A. [3 ,4 ]
机构
[1] Istanbul Medipol Univ, Ataturk Caddesi 40,Guney Kampus, TR-34815 Istanbul, Turkey
[2] Bahrain Univ, Southern Governorate, Bahrain
[3] Qassim Univ, Qasim, Saudi Arabia
[4] Ain Shams Univ, Cairo, Egypt
关键词
Green tea; hypertension; left ventricular hypertrophy; pulse pressure; INDEPENDENT RISK-FACTOR; CORONARY-HEART-DISEASE; BLOOD-PRESSURE; CARDIAC-HYPERTROPHY; CARDIOVASCULAR-DISEASE; RAT MODEL; MORTALITY; DYSFUNCTION; PREDICTOR; EXTRACT;
D O I
10.14814/phy2.14030
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
This study characterized the effects of regular green tea (GT) and hot water (HW) ingestion on systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), and left ventricular hypertrophy (LVH) in two equal, sex- and age-matched groups; Grp1 and Grp2 (n = 100 each; age 53 +/- 4 years) of hypertensive patients. Grp1 had regular GT treatment, followed by HW ingestion, whereas Grp2 had HW ingestion followed by GT treatment for periods of 4 months each. Electrocardiographic (ECG) and echocardiographic assessments of LVH were made before and at the end of both periods. SBP was lowered significantly by 6.6%; DBP by 5.1%, and PP by 9.1% by the end of month 4 of GT treatment in Grp1. Upon GT cessation and HW ingestion, SBP, DBP, and PP returned to pretreatment levels over 4 months. In Grp2, SBP, DBP, and PP were reduced insignificantly by 1.5%, 1.0%, and 2.3% by the end of the 4th month of HW ingestion. Conversely, over 4 months of GT treatment, SBP, DBP, and PP were significantly lowered by 5.4%, 4.1%, and 7.7% from the baseline values, respectively. ECG and echocardiographic evidence of LVH was shown in 20% of Grp1 and 24% of Grp2 patients before intervention. This was significantly lowered to 8% and 10% in Grp1 and Grp2 by GT treatment. However, this increased to 16% following HW ingestion in Grp1. HW ingestion did mot induce regression of LVH in Grp2. Thus, regular GT ingestion has cardiovascular protective effects.
引用
收藏
页数:9
相关论文
共 34 条
[21]   Does tea affect cardiovascular disease? A meta-analysis [J].
Peters, U ;
Poole, C ;
Arab, L .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2001, 154 (06) :495-503
[22]   EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR [J].
Potenza, Maria A. ;
Marasciulo, Flora L. ;
Tarquinio, Mariela ;
Tiravanti, Edy ;
Colantuono, Giuseppe ;
Federici, Antonio ;
Kim, Jeong-a ;
Quon, Michael J. ;
Montagnani, Monica .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2007, 292 (05) :E1378-E1387
[23]   Effect of green tea extract on cardiac hypertrophy following 5/6 nephrectomy in the rat [J].
Priyadarshi, S ;
Valentine, B ;
Han, C ;
Fedorova, OV ;
Bagrov, AY ;
Liu, J ;
Periyasamy, SM ;
Kennedy, D ;
Malhotra, D ;
Xie, ZJ ;
Shapiro, JI .
KIDNEY INTERNATIONAL, 2003, 63 (05) :1785-1790
[24]   Diastolic blood pressure and mortality in the elderly with cardiovascular disease [J].
Protogerou, Athanase D. ;
Safar, Michel E. ;
Iaria, Pierre ;
Safar, Helene ;
Le Dudal, Katia ;
Filipovsky, Jan ;
Henry, Olivier ;
Ducimetiere, Pierre ;
Blacher, Jacques .
HYPERTENSION, 2007, 50 (01) :172-180
[25]   Impact of Achieved Blood Pressure on First Stroke in Uncomplicated Grade 1 Hypertension [J].
Qin, Xianhui ;
Li, Youbao ;
Sun, Ningling ;
He, Mingli ;
Tang, Genfu ;
Yin, Delu ;
Wang, JiGuang ;
Liang, Min ;
Wang, Binyan ;
Huo, Yong ;
Xu, Xin ;
Xu, Xiping ;
Hou, Fan Fan .
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2017, 6 (03)
[26]   Early regression of left ventricular hypertrophy after treatment with esmolol in an experimental rat model of primary hypertension [J].
Quintana-Villamandos, Begona ;
Jesus Delgado-Martos, Maria ;
Javier Sanchez-Hernandez, Jose ;
Juan Gomez de Diego, Jose ;
del Carmen Fernandez-Criado, Maria ;
Canillas, Fernando ;
Martos-Rodriguez, Antonia ;
Delgado-Baeza, Emilio .
HYPERTENSION RESEARCH, 2013, 36 (05) :408-413
[27]   Predictors of high central blood pressure in young with isolated systolic hypertension [J].
Radchenko, G. D. ;
Torbas, O. O. ;
Sirenko, Yu M. .
VASCULAR HEALTH AND RISK MANAGEMENT, 2016, 12 :321-328
[28]   Relationship of Arterial Stiffness Index and Pulse Pressure With Cardiovascular Disease and Mortality [J].
Said, M. Abdullah ;
Eppinga, Ruben N. ;
Lipsic, Erik ;
Verweij, Niek ;
van der Harst, Pim .
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2018, 7 (02)
[29]  
Szulinska M, 2017, FOOD NUTR RES, V61, DOI [10.1080/16546628.2017.1295525, 10.1080/16546628.2017]
[30]   Hypertension and Stroke in Patients with Left Ventricular Assist Devices (LVADs) [J].
Willey, Joshua Z. ;
Boehme, Amelia K. ;
Castagna, Francesco ;
Yuzefpolskaya, Melana ;
Garan, A. Reshad ;
Topkara, Veli ;
Colombo, Paolo C. .
CURRENT HYPERTENSION REPORTS, 2016, 18 (02) :1-6