Effects of conjugated equine estrogen on risk of fractures and BMD in postmenopausal women with hysterectomy: Results from the women's health initiative randomized trial

被引：171
作者：
Jackson, Rebecca D.
Wactawski-Wende, Jean
LaCroix, Andrea Z.
Pettinoer, Mary
Yood, Robert A.
Watts, Nelson B.
Robbins, John A.
Lewis, Cora E.
Beresford, Shirley A. A.
Ko, Marcia G.
Naughton, Michelle J.
Satterfield, Suzanne
Bassford, Tamsen
机构：
[1] Ohio State Univ, Div Endocrinol Diabet & Metab, Columbus, OH 43210 USA
[2] SUNY Buffalo, Buffalo, NY 14260 USA
[3] Fred Hutchinson Canc Res Ctr, Womens Hlth Initiat Clin Coordinating Ctr, Seattle, WA USA
[4] Univ Massachusetts, Sch Med, Worcester, MA USA
[5] Fallon Clin Inc, Worcester, MA USA
[6] Univ Massachusetts, Sch Med, Worcester, MA USA
[7] Univ Cincinnati, Coll Med, Cincinnati, OH USA
[8] Univ Calif Davis, Sch Med, Dept Internal Med, Sacramento, CA 95817 USA
[9] Univ Alabama Birmingham, Div Prevent Med, Birmingham, AL USA
[10] Univ Washington, Seattle, WA 98195 USA
[11] Mayo Clin Scottsdale, Ctr Womens Hlth, Scottsdale, AZ USA
[12] Wake Forest Univ, Bowman Gray Sch Med, Dept Publ Hlth Sci, Winston Salem, NC USA
[13] Univ Tennessee, Dept Prevent Med, Memphis, TN USA
[14] Univ Arizona, Tucson, AZ USA
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2006年 / 21卷 / 06期
关键词：
Women's Health Initiative; estrogen; hormone therapy; fracture; BMD; postmenopause; clinical trial;
D O I：
10.1359/JBMR.060312
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Further analyses from the Women's Health Initiative estrogen trial shows that CEE reduced fracture risk. The fracture reduction at the hip did not differ appreciably among risk strate. These data do not support overall benefit over risk, even in women at highest risk for fracture.
引用
收藏
页码：817 / 828
页数：12
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