Asymmetric total synthesis of botcinic acid and its derivatives: synthetic revision of the structure of botcinolides

被引：12

作者：

Fukui, Hiroki ^{[1
]}

Hitomi, Seiichi ^{[1
]}

Suzuki, Ryo-suke ^{[1
]}

Ikeda, Tatsuhiko ^{[1
]}

Umezaki, Yuma ^{[1
]}

Tsuji, Keisuke ^{[1
]}

Shiina, Isamu ^{[1
]}

机构：

[1] Tokyo Univ Sci, Dept Appl Chem, Fac Sci, Shinjuku Ku, Tokyo 1628601, Japan

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 46期

关键词：

Total synthesis; Botcinin; Botcinic acid; Botcinolide; Structural revision;

D O I：

10.1016/j.tetlet.2008.08.108

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereoselective total syntheses of botcinic acid, botcinic acid methyl ester, 3-O-acetylbotcinic acid methyl ester, botcineric acid, and botcinin E were achieved. The structures of these compounds have been unequivocally determined through their total synthesis, and they are identified with the revised structures of botcinolide, 4-O-methylbotcinolide, 3-O-acetyl-5-O-methylbotcinolide, homobotcinolide, and 2-epilbotcinolide, respectively. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：6514 / 6517

页数：4

共 14 条

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