Allergen immunotherapy in atopic dermatitis: Light and shadow in children

被引：14

作者：

Caminiti, Lucia ^{[1
]}

Panasiti, Ilenia ^{[1
]}

Landi, Massimo ^{[2
]}

De Filippo, Maria ^{[3
]}

Olcese, Roberta ^{[4
]}

Ciprandi, Giorgio ^{[5
]}

Vernich, Mario ^{[6
]}

Carelli, Francesco ^{[7
]}

Votto, Martina ^{[3
]}

Barberi, Salvatore ^{[6
]}

机构：

[1] Univ Messina, Allergy Unit, Dept Paediat, Messina, Italy

[2] Inst Biomed Res & Innovat IRIB, Paediat Natl Healthcare Syst Turin, Turin, Italy

[3] Univ Pavia, Fdn IRCSS Policlin San Matteo, Paediat Clin, Dept Paediat, Pavia, Italy

[4] Ist Giannina Gaslini, Allergy Ctr, Genoa, Italy

[5] Casa Cura Villa Montallegro, Allergy Clin, Genoa, Italy

[6] RHO, ASST Rhodense, Paediat Unit, Milan, Italy

[7] Policlin Giovanni XXIII, Azienza Osped Univ, Paediat Unit, Bari, Italy

来源：

PEDIATRIC ALLERGY AND IMMUNOLOGY | 2020年 / 31卷

关键词：

allergic immunotherapy; Atopic dermatitis; children; GUIDELINES; ECZEMA;

D O I：

10.1111/pai.13390

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Atopic dermatitis (AD) is a chronic remitting-relapsing inflammatory skin disorder. Due to the multifactorial pathogenesis, there are numerous therapeutic management approaches, mainly based on symptomatic treatments. In recent years, allergen immunotherapy (AIT) has been progressively advanced as targeted disease-modifying treatment of allergic disease. The most recent guideline from the American Academy of Dermatology concludes that data available do not support its use in AD. The Joint Task Force and The European Academy of Dermatology suggest that clinicians can consider AIT treatment in selected patients characterized by aeroallergen sensitization, prevalently HDM, severe AD, and clinical exacerbation after exposure to the causative allergen. Nevertheless, its role in AD is still under debate, especially in children.

引用

页码：46 / 48

页数：3

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